Merkens Helen相关文献与解析，生知库 | 链接生命科学的每一步

Kwon, Daniel; Bloise, Ingrid; Zhang, Zhengxing; Colpo, Nadine; Wilson, Ryan; Tan, Ruiyan; Merkens, Helen; Zeisler, Jutta; Lau, Joseph; Lin, Kuo-Shyan; Bénard, François

CXCR4

发表日期：2026

文献求助收藏

Call for Papers: The Prodigious Diversity of Lipid Nanoparticles for Gene Delivery

征稿启事：用于基因递送的脂质纳米颗粒的巨大多样性

期刊:ACS Bio & Med Chem Au

影响因子:4.3

doi:10.1021/acsbiomedchemau.5c00224

McNeil, Brooke L; Wharton, Luke; Chen, Chao-Cheng; Merkens, Helen; Čolović, Milena; Rodríguez-Rodríguez, Cristina; Wilson, John; Mair, Stefan; Zhang, Chengcheng; McDonagh, Anthony W; Lin, Kuo-Shyan; Bénard, François; Wuest, Frank; Schaffer, Paul; Ramogida, Caterina F; Lavasanifar, Afsaneh; Cheng, Miffy Hok Yan; Lentacker, Ine

发表日期：2025

文献求助收藏

Synthesis and Evaluation of Novel (68)Ga-Labeled [D-Phe(6),Leu(13)ψThz(14)]bombesin(6-14) Analogs for Cancer Imaging with Positron Emission Tomography

新型(68)Ga标记的[D-Phe(6),Leu(13)ψTzh(14)]铃蟾肽(6-14)类似物的合成与评价及其在正电子发射断层扫描癌症成像中的应用

期刊:Pharmaceuticals

影响因子:4.8

doi:10.3390/ph17050621

Wang, Lei; Chen, Chao-Cheng; Zhang, Zhengxing; Kuo, Hsiou-Ting; Zhang, Chengcheng; Colpo, Nadine; Merkens, Helen; Bénard, François; Lin, Kuo-Shyan

Exploration of commercial cyclen-based chelators for mercury-197 m/g incorporation into theranostic radiopharmaceuticals

探索商业化的环烯基螯合剂在治疗诊断放射性药物中掺入汞-197 m/g 的应用

期刊:Frontiers in Chemistry

影响因子:4.2

doi:10.3389/fchem.2024.1292566

Randhawa, Parmissa; Carbo-Bague, Imma; Davey, Patrick R W J; Chen, Shaohuang; Merkens, Helen; Uribe, Carlos F; Zhang, Chengcheng; Tosato, Marianna; Bénard, François; Radchenko, Valery; Ramogida, Caterina F

发表日期：2024

文献求助收藏

First preclinical SPECT/CT imaging and biodistribution of [(165)Er]ErCl(3) and [(165)Er]Er-PSMA-617.

[(165)Er]ErCl(3) 和 [(165)Er]Er-PSMA-617 的首次临床前 SPECT/CT 成像和生物分布

期刊:EJNMMI Radiopharmacy and Chemistry

影响因子:3.3

doi:10.1186/s41181-024-00312-9

Saeedi Saghez Behrad, RodrÃguez-RodrÃguez Cristina, Esquinas Pedro Luis, Merkens Helen, BÃ©nard FranÃ§ois, Radchenko Valery, Yang Hua

发表日期：2024

文献求助收藏

PSMA imaging as a non-invasive tool to monitor inducible gene expression in vivo

PSMA成像作为一种非侵入性工具，可用于监测体内诱导基因表达。

期刊:Ejnmmi Research

影响因子:3

doi:10.1186/s13550-023-01063-5

Simunic, Marin; Joshi, Jay T; Merkens, Helen; Colpo, Nadine; Kuo, Hsiou-Ting; Lum, Julian J; Bénard, François

发表日期：2024

文献求助收藏

Lys-urea-Aad, Lys-urea-Cmc and Lys-urea-Cms as potential pharmacophores for the design of PSMA-targeted radioligands to reduce off-target uptake in kidneys and salivary glands

Lys-urea-Aad、Lys-urea-Cmc 和 Lys-urea-Cms 作为潜在的药效团，可用于设计 PSMA 靶向放射性配体，以减少肾脏和唾液腺中的脱靶吸收。

期刊:Theranostics

影响因子:13.3

doi:10.7150/thno.87663

Kuo, Hsiou-Ting; Zhang, Zhengxing; Zhang, Chengcheng; Merkens, Helen; Tan, Ruiyan; Wong, Antonio A W L; Uribe, Carlos F; Bénard, François; Lin, Kuo-Shyan

发表日期：2023

文献求助收藏

Preclinical Evaluation of [(155/161)Tb]Tb-Crown-TATE-A Novel SPECT Imaging Theranostic Agent Targeting Neuroendocrine Tumours

[(155/161)Tb]Tb-Crown-TATE-A 新型 SPECT 成像诊疗剂靶向神经内分泌肿瘤的临床前评估

期刊:Molecules

影响因子:4.6

doi:10.3390/molecules28073155

Wharton, Luke; McNeil, Scott W; Merkens, Helen; Yuan, Zheliang; Van de Voorde, Michiel; Engudar, Gokce; Ingham, Aidan; Koniar, Helena; Rodríguez-Rodríguez, Cristina; Radchenko, Valery; Ooms, Maarten; Kunz, Peter; Bénard, François; Schaffer, Paul; Yang, Hua

(68)Ga-Labeled [Thz(14)]Bombesin(7-14) Analogs: Promising GRPR-Targeting Agonist PET Tracers with Low Pancreas Uptake

(68)Ga标记的[Thz(14)]铃蟾肽(7-14)类似物：具有低胰腺摄取率的、有前景的GRPR靶向激动剂PET示踪剂。

期刊:Molecules

影响因子:4.6

doi:10.3390/molecules28041977

Wang, Lei; Bratanovic, Ivica Jerolim; Zhang, Zhengxing; Kuo, Hsiou-Ting; Merkens, Helen; Zeisler, Jutta; Zhang, Chengcheng; Tan, Ruiyan; Bénard, François; Lin, Kuo-Shyan

发表日期：2023

文献求助收藏

What a difference a methylene makes: replacing Glu with Asp or Aad in the Lys-urea-Glu pharmacophore of PSMA-targeting radioligands to reduce kidney and salivary gland uptake

一个亚甲基就能带来如此巨大的改变：在PSMA靶向放射性配体的赖氨酸-尿素-谷氨酸药效团中，用天冬氨酸或腺苷酸取代谷氨酸，即可降低肾脏和唾液腺的摄取。

期刊:Theranostics

影响因子:13.3

doi:10.7150/thno.76571

Kuo, Hsiou-Ting; Lin, Kuo-Shyan; Zhang, Zhengxing; Zhang, Chengcheng; Merkens, Helen; Tan, Ruiyan; Roxin, Aron; Uribe, Carlos F; Bénard, François

发表日期：2022

文献求助收藏

Development of an Optimized CXCR4-Targeting Theranostic Pair

开发优化的CXCR4靶向诊疗组合

Call for Papers: The Prodigious Diversity of Lipid Nanoparticles for Gene Delivery

征稿启事：用于基因递送的脂质纳米颗粒的巨大多样性

Synthesis and Evaluation of Novel (68)Ga-Labeled [D-Phe(6),Leu(13)ψThz(14)]bombesin(6-14) Analogs for Cancer Imaging with Positron Emission Tomography

新型(68)Ga标记的[D-Phe(6),Leu(13)ψTzh(14)]铃蟾肽(6-14)类似物的合成与评价及其在正电子发射断层扫描癌症成像中的应用

Exploration of commercial cyclen-based chelators for mercury-197 m/g incorporation into theranostic radiopharmaceuticals

探索商业化的环烯基螯合剂在治疗诊断放射性药物中掺入汞-197 m/g 的应用

First preclinical SPECT/CT imaging and biodistribution of [(165)Er]ErCl(3) and [(165)Er]Er-PSMA-617.

[(165)Er]ErCl(3) 和 [(165)Er]Er-PSMA-617 的首次临床前 SPECT/CT 成像和生物分布

PSMA imaging as a non-invasive tool to monitor inducible gene expression in vivo

PSMA成像作为一种非侵入性工具，可用于监测体内诱导基因表达。

Lys-urea-Aad, Lys-urea-Cmc and Lys-urea-Cms as potential pharmacophores for the design of PSMA-targeted radioligands to reduce off-target uptake in kidneys and salivary glands

Lys-urea-Aad、Lys-urea-Cmc 和 Lys-urea-Cms 作为潜在的药效团，可用于设计 PSMA 靶向放射性配体，以减少肾脏和唾液腺中的脱靶吸收。

Preclinical Evaluation of [(155/161)Tb]Tb-Crown-TATE-A Novel SPECT Imaging Theranostic Agent Targeting Neuroendocrine Tumours

[(155/161)Tb]Tb-Crown-TATE-A 新型 SPECT 成像诊疗剂靶向神经内分泌肿瘤的临床前评估

(68)Ga-Labeled [Thz(14)]Bombesin(7-14) Analogs: Promising GRPR-Targeting Agonist PET Tracers with Low Pancreas Uptake

(68)Ga标记的[Thz(14)]铃蟾肽(7-14)类似物：具有低胰腺摄取率的、有前景的GRPR靶向激动剂PET示踪剂。

What a difference a methylene makes: replacing Glu with Asp or Aad in the Lys-urea-Glu pharmacophore of PSMA-targeting radioligands to reduce kidney and salivary gland uptake

一个亚甲基就能带来如此巨大的改变：在PSMA靶向放射性配体的赖氨酸-尿素-谷氨酸药效团中，用天冬氨酸或腺苷酸取代谷氨酸，即可降低肾脏和唾液腺的摄取。