Merkwirth相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Mezagitamab in systemic lupus erythematosus: clinical and mechanistic findings of CD38 inhibition in an autoimmune disease

Mezagitamab治疗系统性红斑狼疮：自身免疫性疾病中CD38抑制的临床和机制研究

期刊:Lupus Science & Medicine

影响因子:3.5

doi:10.1136/lupus-2023-001112

McDonnell, Scott R P; Nguyen, Van Anh; Walton, Noah M; Merkwirth, Carsten; Hong, Feng; Berg, Deborah; Muensterman, Elena Tomaselli; Furie, Richard A

自身免疫性疾病

免疫/内分泌

发表日期：2024

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Molecular characterization of type I IFN-induced cytotoxicity in bladder cancer cells reveals biomarkers of resistance

膀胱癌细胞中 I 型干扰素诱导的细胞毒性的分子表征揭示了耐药性的生物标志物

期刊:Molecular Therapy-Oncolytics

影响因子:5.3

doi:10.1016/j.omto.2021.11.006

Jennifer L Green, Robin E Osterhout, Amy L Klova, Carsten Merkwirth, Scott R P McDonnell, Reza Beheshti Zavareh, Bryan C Fuchs, Adeela Kamal, Jørn S Jakobsen

发表日期：2021

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Two Conserved Histone Demethylases Regulate Mitochondrial Stress-Induced Longevity

两种保守的组蛋白去甲基化酶调控线粒体应激诱导的寿命

影响因子:42.5

doi:10.1016/j.cell.2016.04.012

Merkwirth, Carsten; Jovaisaite, Virginija; Durieux, Jenni; Matilainen, Olli; Jordan, Sabine D; Quiros, Pedro M; Steffen, Kristan K; Williams, Evan G; Mouchiroud, Laurent; Tronnes, Sarah U; Murillo, Virginia; Wolff, Suzanne C; Shaw, Reuben J; Auwerx, Johan; Dillin, Andrew

发表日期：2016

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Loss of OMA1 delays neurodegeneration by preventing stress-induced OPA1 processing in mitochondria

OMA1 的缺失通过阻止线粒体中应激诱导的 OPA1 处理来延缓神经退行性病变

期刊:Journal of Cell Biology

影响因子:7.4

doi:10.1083/jcb.201507022

Anne Korwitz, Carsten Merkwirth, Ricarda Richter-Dennerlein, Simon E Tröder, Hans-Georg Sprenger, Pedro M Quirós, Carlos López-Otín, Elena I Rugarli, Thomas Langer

发表日期：2016

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Inhibition of insulin/IGF-1 receptor signaling protects from mitochondria-mediated kidney failure

抑制胰岛素/IGF-1受体信号可预防线粒体介导的肾衰竭

期刊:EMBO Molecular Medicine

doi:10.15252/emmm.201404916

Christina Ising, Sybille Koehler, Sebastian Brähler, Carsten Merkwirth, Martin Höhne, Olivier R Baris, Henning Hagmann, Martin Kann, Francesca Fabretti, Claudia Dafinger, Wilhelm Bloch, Bernhard Schermer, Andreas Linkermann, Jens C Brüning, Christine E Kurschat, Roman-Ulrich Müller, Rudolf J Wiesner

Insulin Receptor

发表日期：2015

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Loss of prohibitin induces mitochondrial damages altering β-cell function and survival and is responsible for gradual diabetes development

抑制蛋白的缺失会导致线粒体损伤，从而改变β细胞的功能和存活，并最终导致糖尿病的逐渐发生。

期刊:Diabetes

影响因子:6.2

doi:10.2337/db13-0152

Sachin Supale ，Fabrizio Thorel, Carsten Merkwirth, Asllan Gjinovci, Pedro L Herrera, Luca Scorrano, Paolo Meda, Thomas Langer, Pierre Maechler

细胞生物学

发表日期：2013

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Increased proteasome activity in human embryonic stem cells is regulated by PSMD11.

人类胚胎干细胞中蛋白酶体活性的增加受PSMD11调控

影响因子:48.5

doi:10.1038/nature11468

Vilchez David, Boyer Leah, Morantte Ianessa, Lutz Margaret, Merkwirth Carsten, Joyce Derek, Spencer Brian, Page Lesley, Masliah Eliezer, Berggren W Travis, Gage Fred H, Dillin Andrew

发育与干细胞

细胞生物学

发表日期：2012

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SLP-2 is required for stress-induced mitochondrial hyperfusion

SLP-2 是应激诱导的线粒体高灌注所必需的

期刊:EMBO Journal

影响因子:9.4

doi:10.1038/emboj.2009.89

Daniel Tondera, Stéphanie Grandemange, Alexis Jourdain, Mariusz Karbowski, Yves Mattenberger, Sébastien Herzig, Sandrine Da Cruz, Pascaline Clerc, Ines Raschke, Carsten Merkwirth, Sarah Ehses, Frank Krause, David C Chan, Christiane Alexander, Christoph Bauer, Richard Youle, Thomas Langer, Jean-Claud

发表日期：2009

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Prohibitins control cell proliferation and apoptosis by regulating OPA1-dependent cristae morphogenesis in mitochondria

抑制蛋白通过调节线粒体中 OPA1 依赖的嵴形态发生来控制细胞增殖和凋亡。

期刊:Genes & Development

影响因子:7.7

doi:10.1101/gad.460708

Merkwirth, Carsten; Dargazanli, Sascha; Tatsuta, Takashi; Geimer, Stefan; Löwer, Beatrix; Wunderlich, F Thomas; von Kleist-Retzow, Jürgen-Christoph; Waisman, Ari; Westermann, Benedikt; Langer, Thomas

细胞生物学

发表日期：2008

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Thrombin inhibitors identified by computer-assisted multiparameter design

通过计算机辅助多参数设计鉴定的凝血酶抑制剂

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.0501983102

Riester, Daniel; Wirsching, Frank; Salinas, Gabriela; Keller, Martina; Gebinoga, Michael; Kamphausen, Stefan; Merkwirth, Christian; Goetz, Ruediger; Wiesenfeldt, Martin; Stürzebecher, Jörg; Bode, Wolfram; Friedrich, Rainer; Thürk, Marcel; Schwienhorst, Andreas

发表日期：2005

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