Mern相关文献与解析，生知库 | 链接生命科学的每一步

Collagen II enrichment through scAAV6-RNAi-mediated inhibition of matrix-metalloproteinases 3 and 13 in degenerative nucleus-pulposus cells degenerative disc disease and biological treatment strategies

通过 scAAV6-RNAi 介导抑制退行性髓核细胞中的基质金属蛋白酶 3 和 13 来富集 II 型胶原蛋白、退行性椎间盘疾病和生物治疗策略

期刊:Experimental Biology and Medicine

影响因子:

doi:10.3389/ebm.2024.10048

Demissew Shenegelegn Mern, Claudius Thomé

Synergetic enrichment of aggrecan in nucleus pulposus cells by scAAV6-shRNA-mediated knockdown of aggrecanase-1 and aggrecanase-2

通过 scAAV6-shRNA 介导的聚集蛋白聚糖酶-1 和聚集蛋白聚糖酶-2 敲低，在髓核细胞中协同富集聚集蛋白聚糖

期刊:Experimental Biology and Medicine

影响因子:

doi:10.1177/15353702231171905

Demissew Shenegelegn Mern, Claudius Thomé

Matcha Green Tea Powder does not Prevent Diet-Induced Arteriosclerosis in New Zealand White Rabbits Due to Impaired Reverse Cholesterol Transport

抹茶绿茶粉不能预防新西兰白兔因胆固醇逆向转运受损而引起的饮食诱发动脉硬化

期刊:Molecular Nutrition & Food Research

影响因子:4.5

doi:10.1002/mnfr.202100371

Monika Hunjadi, Claudia Sieder, Anja Beierfuß, Christian Kremser, Bernhard Moriggl, René Welte, Christine Kastner, Demissew Shenegelegn Mern, Andreas Ritsch

Animal models of regenerative medicine for biological treatment approaches of degenerative disc diseases

用于治疗椎间盘退行性疾病的再生医学生物疗法的动物模型

期刊:Experimental Biology and Medicine

影响因子:2.7

doi:10.1177/1535370220969123

Mern, Demissew Shenegelegn; Walsen, Tanja; Beierfuß, Anja; Thomé, Claudius

发育与干细胞

发表日期：2021

文献求助收藏

APOE-knockout in rabbits causes loss of cells in nucleus pulposus and enhances the levels of inflammatory catabolic cytokines damaging the intervertebral disc matrix

兔子的 APOE 基因敲除导致髓核细胞丢失，并增加了破坏椎间盘基质的炎性分解代谢细胞因子的水平

期刊:PLoS One

影响因子:2.9

doi:10.1371/journal.pone.0225527

Anja Beierfuß, Monika Hunjadi, Andreas Ritsch, Christian Kremser, Claudius Thomé, Demissew Shenegelegn Mern

Self-complementary adeno-associated virus serotype 6 mediated knockdown of ADAMTS4 induces long-term and effective enhancement of aggrecan in degenerative human nucleus pulposus cells: A new therapeutic approach for intervertebral disc disorders

自互补腺相关病毒血清型 6 介导的 ADAMTS4 敲低可诱导退行性人类髓核细胞中聚集蛋白聚糖的长期有效增强：一种治疗椎间盘疾病的新方法

期刊:PLoS One

影响因子:2.9

doi:10.1371/journal.pone.0172181

Demissew Shenegelegn Mern, Anja Tschugg, Sebastian Hartmann, Claudius Thomé

Knockout of Apolipoprotein E in rabbit promotes premature intervertebral disc degeneration: A new in vivo model for therapeutic approaches of spinal disc disorders

兔子体内载脂蛋白 E 的敲除会促进椎间盘过早退化：一种治疗椎间盘疾病的新型体内模型

期刊:PLoS One

影响因子:2.9

doi:10.1371/journal.pone.0187564

Anja Beierfuß, Hermann Dietrich, Christian Kremser, Monika Hunjadi, Andreas Ritsch, Thomas Rülicke, Claudius Thomé, Demissew Shenegelegn Mern

Identification and characterization of human nucleus pulposus cell specific serotypes of adeno-associated virus for gene therapeutic approaches of intervertebral disc disorders

腺相关病毒人类髓核细胞特异性血清型的鉴定和特性分析，用于椎间盘疾病的基因治疗方法

期刊:BMC Musculoskeletal Disorders

影响因子:2.2

doi:10.1186/s12891-015-0799-4

Demissew S Mern, Claudius Thomé

Imbalanced protein expression patterns of anabolic, catabolic, anti-catabolic and inflammatory cytokines in degenerative cervical disc cells: new indications for gene therapeutic treatments of cervical disc diseases

退行性颈椎间盘细胞中合成代谢、分解代谢、抗分解代谢和炎性细胞因子的蛋白质表达模式不平衡：颈椎间盘疾病基因治疗的新指征

期刊:PLoS One

影响因子:2.9

doi:10.1371/journal.pone.0096870

Demissew S Mern, Anja Beierfuβ, Johann Fontana, Claudius Thomé, Aldemar A Hegewald

Genomic selection for crop improvement in fruits and vegetables: a systematic scoping review

果蔬作物改良的基因组选择：系统性范围综述

Collagen II enrichment through scAAV6-RNAi-mediated inhibition of matrix-metalloproteinases 3 and 13 in degenerative nucleus-pulposus cells degenerative disc disease and biological treatment strategies

通过 scAAV6-RNAi 介导抑制退行性髓核细胞中的基质金属蛋白酶 3 和 13 来富集 II 型胶原蛋白、退行性椎间盘疾病和生物治疗策略

Synergetic enrichment of aggrecan in nucleus pulposus cells by scAAV6-shRNA-mediated knockdown of aggrecanase-1 and aggrecanase-2

通过 scAAV6-shRNA 介导的聚集蛋白聚糖酶-1 和聚集蛋白聚糖酶-2 敲低，在髓核细胞中协同富集聚集蛋白聚糖

Matcha Green Tea Powder does not Prevent Diet-Induced Arteriosclerosis in New Zealand White Rabbits Due to Impaired Reverse Cholesterol Transport

抹茶绿茶粉不能预防新西兰白兔因胆固醇逆向转运受损而引起的饮食诱发动脉硬化

Animal models of regenerative medicine for biological treatment approaches of degenerative disc diseases

用于治疗椎间盘退行性疾病的再生医学生物疗法的动物模型

APOE-knockout in rabbits causes loss of cells in nucleus pulposus and enhances the levels of inflammatory catabolic cytokines damaging the intervertebral disc matrix

兔子的 APOE 基因敲除导致髓核细胞丢失，并增加了破坏椎间盘基质的炎性分解代谢细胞因子的水平

Self-complementary adeno-associated virus serotype 6 mediated knockdown of ADAMTS4 induces long-term and effective enhancement of aggrecan in degenerative human nucleus pulposus cells: A new therapeutic approach for intervertebral disc disorders

自互补腺相关病毒血清型 6 介导的 ADAMTS4 敲低可诱导退行性人类髓核细胞中聚集蛋白聚糖的长期有效增强：一种治疗椎间盘疾病的新方法

Knockout of Apolipoprotein E in rabbit promotes premature intervertebral disc degeneration: A new in vivo model for therapeutic approaches of spinal disc disorders

兔子体内载脂蛋白 E 的敲除会促进椎间盘过早退化：一种治疗椎间盘疾病的新型体内模型

Identification and characterization of human nucleus pulposus cell specific serotypes of adeno-associated virus for gene therapeutic approaches of intervertebral disc disorders

腺相关病毒人类髓核细胞特异性血清型的鉴定和特性分析，用于椎间盘疾病的基因治疗方法

Imbalanced protein expression patterns of anabolic, catabolic, anti-catabolic and inflammatory cytokines in degenerative cervical disc cells: new indications for gene therapeutic treatments of cervical disc diseases

退行性颈椎间盘细胞中合成代谢、分解代谢、抗分解代谢和炎性细胞因子的蛋白质表达模式不平衡：颈椎间盘疾病基因治疗的新指征