日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Lipid Nanoparticle Fas Gene Therapy Suppresses Autoimmune Lymphoproliferative Syndrome in Mice

脂质纳米颗粒Fas基因疗法抑制小鼠自身免疫性淋巴增生综合征

Poschel, Dakota B; Tiamiyu, Zainab; Redd, Priscilla; Merting, Alyssa; Savage, Natasha; Liu, Kebin

PD-L1 restrains PD-1+Nrp1lo Treg cells to suppress inflammation-driven colorectal tumorigenesis

PD-L1抑制PD-1+Nrp1lo Treg细胞,从而抑制炎症驱动的结直肠肿瘤发生

Dakota B Poschel ,John D Klement ,Alyssa D Merting ,Chunwan Lu ,Yang Zhao ,Dafeng Yang ,Wei Xiao ,Huabin Zhu ,Ponnala Rajeshwari ,Michael Toscano ,Kimya Jones ,Amanda Barrett ,Roni J Bollag ,Padraic G Fallon ,Huidong Shi ,Kebin Liu

In vitro antibody-mediated SARS-CoV-2 infection suppression through human ACE2 receptor blockade

体外抗体介导的SARS-CoV-2感染抑制是通过阻断人ACE2受体实现的

Priscilla S Redd,Alyssa D Merting,John D Klement,Dakota B Poschel,Dafeng Yang,Kebin Liu

Tumor PD-L1 engages myeloid PD-1 to suppress type I interferon to impair cytotoxic T lymphocyte recruitment

肿瘤PD-L1与髓系PD-1结合,抑制I型干扰素,从而削弱细胞毒性T淋巴细胞的募集。

John D Klement ,Priscilla S Redd ,Chunwan Lu ,Alyssa D Merting ,Dakota B Poschel ,Dafeng Yang ,Natasha M Savage ,Gang Zhou ,David H Munn ,Padraic G Fallon ,Kebin Liu

IRF8 Regulates Intrinsic Ferroptosis through Repressing p53 Expression to Maintain Tumor Cell Sensitivity to Cytotoxic T Lymphocytes

IRF8 通过抑制 p53 表达来调节内在铁死亡以维持肿瘤细胞对细胞毒性 T 淋巴细胞的敏感性

Dakota B Poschel, Mercy Kehinde-Ige, John D Klement, Dafeng Yang, Alyssa D Merting, Natasha M Savage, Huidong Shi, Kebin Liu

Lipid Nanoparticle Delivery of Fas Plasmid Restores Fas Expression to Suppress Melanoma Growth In Vivo

脂质纳米粒子递送 Fas 质粒恢复 Fas 表达以抑制体内黑色素瘤生长

Zeinab Y Al Subeh, Dakota B Poschel, Priscilla S Redd, John D Klement, Alyssa D Merting, Dafeng Yang, Megh Mehta, Huidong Shi, Yolonda L Colson, Nicholas H Oberlies, Cedric J Pearce, Aaron H Colby, Mark W Grinstaff, Kebin Liu

Pilot-scale production of expansile nanoparticles: Practical methods for clinical scale-up

膨胀型纳米粒子的中试规模生产:临床放大生产的实用方法

Colby, Aaron H; Liu, Rong; Doyle, Robert P; Merting, Alyssa; Zhang, Heng; Savage, Natasha; Chu, Ngoc-Quynh; Hollister, Beth A; McCulloch, William; Burdette, Joanna E; Pearce, Cedric J; Liu, Kebin; Oberlies, Nicholas H; Colson, Yolonda L; Grinstaff, Mark W

WDR5-H3K4me3 epigenetic axis regulates OPN expression to compensate PD-L1 function to promote pancreatic cancer immune escape

WDR5-H3K4me3表观遗传轴调控OPN表达补偿PD-L1功能促进胰腺癌免疫逃逸

Chunwan Lu, Zhuoqi Liu, John D Klement, Dafeng Yang, Alyssa D Merting, Dakota Poschel, Thomas Albers, Jennifer L Waller, Huidong Shi, Kebin Liu

Osteopontin Blockade Immunotherapy Increases Cytotoxic T Lymphocyte Lytic Activity and Suppresses Colon Tumor Progression

骨桥蛋白阻断免疫疗法可增强细胞毒性T淋巴细胞的溶解活性并抑制结肠肿瘤进展

Klement, John D; Poschel, Dakota B; Lu, Chunwan; Merting, Alyssa D; Yang, Dafeng; Redd, Priscilla S; Liu, Kebin