日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Dose Selection for DuoBody®-CD40x4-1BB (GEN1042/BNT312) Using a mPBPK/RO Model Leveraging Preclinical and Clinical Data

利用临床前和临床数据,采用 mPBPK/RO 模型选择 DuoBody®-CD40x4-1BB (GEN1042/BNT312) 的剂量

Bajaj, Gaurav; Shchelokov, Dmitry; Demin, Oleg Jr; Adams, Homer C 3rd; Feng, Yan; Gibiansky, Leonid; van der Lee, Saskia; Johri, Anandhi; Belete, Merzu; Muik, Alexander; Panorchan, Porntula; Türeci, Özlem; Sahin, Uğur; Ahmadi, Tahamtan; Gupta, Manish; Demin, Oleg; Thalhauser, Craig

Deep computational image analysis of immune cell niches reveals treatment-specific outcome associations in lung cancer

对免疫细胞微环境进行深度计算图像分析,揭示肺癌治疗特异性结果关联

Barrera, Cristian; Corredor, Germán; Viswanathan, Vidya Sankar; Ding, Ruiwen; Toro, Paula; Fu, Pingfu; Buzzy, Christina; Lu, Cheng; Velu, Priya; Zens, Philipp; Berezowska, Sabina; Belete, Merzu; Balli, David; Chang, Han; Baxi, Vipul; Syrigos, Konstantinos; Rimm, David L; Velcheti, Vamsidhar; Schalper, Kurt; Romero, Eduardo; Madabhushi, Anant

Estradiol-mediated protection against high-fat diet induced anxiety and obesity is associated with changes in the gut microbiota in female mice.

雌二醇介导的对高脂饮食引起的焦虑和肥胖的保护作用与雌性小鼠肠道菌群的变化有关

Acharya Kalpana D, Graham Madeline, Raman Harshini, Parakoyi Abigail E R, Corcoran Alexis, Belete Merzu, Ramaswamy Bharath, Koul Shashikant, Sachar Ishneet, Derendorf Kevin, Wilmer Jeremy B, Gottipati Srikanth, Tetel Marc J

Image analysis reveals molecularly distinct patterns of TILs in NSCLC associated with treatment outcome

图像分析揭示了非小细胞肺癌中肿瘤浸润淋巴细胞(TILs)的分子特征模式与治疗结果相关

Ding, Ruiwen; Prasanna, Prateek; Corredor, Germán; Barrera, Cristian; Zens, Philipp; Lu, Cheng; Velu, Priya; Leo, Patrick; Beig, Niha; Li, Haojia; Toro, Paula; Berezowska, Sabina; Baxi, Vipul; Balli, David; Belete, Merzu; Rimm, David L; Velcheti, Vamsidhar; Schalper, Kurt; Madabhushi, Anant

Genetic and stochastic influences upon tumor formation and tumor types in Li-Fraumeni mouse models

遗传和随机因素对李-弗劳梅尼小鼠模型中肿瘤形成和肿瘤类型的影响

Chan, Chang S; Sun, Yvonne; Ke, Hua; Zhao, Yuhan; Belete, Merzu; Zhang, Cen; Feng, Zhaohui; Levine, Arnold J; Hu, Wenwei