日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Sterol biosynthesis regulates TLR signaling and the innate immune response in a Smith-Lemli-Opitz syndrome model

在史密斯-莱姆利-奥皮茨综合征模型中,甾醇生物合成调节TLR信号传导和先天免疫反应。

Gabor, Kristin; Mesev, Emily V; Madenspacher, Jennifer; Meacham, Julie; Rai, Prashant; Moon, Sookjin; Wassif, Christopher A; Shaikh, Saame Raza; Tucker, C J; Karmaus, Peer; Bianconi, Simona; Porter, Forbes D; Fessler, Michael B

Engineered chimeric receptors for dissecting interferon signaling

用于解析干扰素信号传导的工程化嵌合受体

Lin, Aaron E; Mesev, Emily V; Toettcher, Jared E; Ploss, Alexander

pYtags enable spatiotemporal measurements of receptor tyrosine kinase signaling in living cells

pYtags 可以对活细胞中的受体酪氨酸激酶信号进行时空测量

Payam E Farahani, Xiaoyu Yang, Emily V Mesev, Kaylan A Fomby, Ellen H Brumbaugh-Reed, Caleb J Bashor, Celeste M Nelson, Jared E Toettcher

Synthetic Heterodimers of Type III Interferon Receptors Require TYK2 for STAT Activation

合成的 III 型干扰素受体异二聚体需要 TYK2 来激活 STAT

Emily V Mesev, Emma G Guare, Alexander Ploss, Jared E Toettcher

Membrane-proximal motifs encode differences in signaling strength between type I and III interferon receptors

膜近端基序编码 I 型和 III 型干扰素受体之间的信号强度差异

Emily V Mesev, Aaron E Lin, Emma G Guare, Brigitte L Heller, Florian Douam, Britt Adamson, Jared E Toettcher, Alexander Ploss

Selective induction of P-glycoprotein at the CNS barriers during symptomatic stage of an ALS animal model

在 ALS 动物模型的症状阶段,在中枢神经系统屏障处选择性诱导 P-糖蛋白

Gary N Y Chan, Rebecca A Evans, David B Banks, Emily V Mesev, David S Miller, Ronald E Cannon

Vesicular stomatitis virus expressing interferon-β is oncolytic and promotes antitumor immune responses in a syngeneic murine model of non-small cell lung cancer

表达干扰素-β的水泡性口炎病毒具有溶瘤作用,并在非小细胞肺癌同基因小鼠模型中促进抗肿瘤免疫反应

Manish R Patel, Blake A Jacobson, Yan Ji, Jeremy Drees, Shaogeng Tang, Kerry Xiong, Hengbing Wang, Jennifer E Prigge, Alexander S Dash, Andrea K Kratzke, Emily Mesev, Ryan Etchison, Mark J Federspiel, Stephen J Russell, Robert A Kratzke