日期 影响因子
日期:
2020 年 — 2026 年
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影响因子:
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The SOCS box of suppressor of cytokine signaling-1 is important for inhibition of cytokine action in vivo

细胞因子信号抑制因子-1的SOCS盒对于体内细胞因子活性的抑制至关重要。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.231486498
Zhang, J G; Metcalf, D; Rakar, S; Asimakis, M; Greenhalgh, C J; Willson, T A; Starr, R; Nicholson, S E; Carter, W; Alexander, W S; Hilton, D J; Nicola, N A
信号转导
细胞生物学
免疫/内分泌
发表日期：2001
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Functional analysis of Asb-1 using genetic modification in mice.

利用基因改造小鼠对Asb-1进行功能分析

期刊:Molecular and Cellular Biology
影响因子:2.7
doi:10.1128/MCB.21.18.6189-6197.2001
Kile B T, Metcalf D, Mifsud S, DiRago L, Nicola N A, Hilton D J, Alexander W S
发表日期：2001
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Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130

细胞因子信号抑制因子-3优先结合于共享细胞因子受体亚基gp130上的SHP-2结合位点

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.100135197
Nicholson, S E; De Souza, D; Fabri, L J; Corbin, J; Willson, T A; Zhang, J G; Silva, A; Asimakis, M; Farley, A; Nash, A D; Metcalf, D; Hilton, D J; Nicola, N A; Baca, M
信号转导
SHP-2
gp130
细胞生物学
免疫/内分泌
发表日期：2000
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The development of fatal myocarditis and polymyositis in mice heterozygous for IFN-gamma and lacking the SOCS-1 gene

在 IFN-γ 杂合子且缺乏 SOCS-1 基因的小鼠中，致命性心肌炎和多发性肌炎的发生发展

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.160255197
Metcalf, D; Di Rago, L; Mifsud, S; Hartley, L; Alexander, W S
心肌炎
IFN-γ
心血管
发表日期：2000
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The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation

细胞因子信号抑制因子中保守的SOCS盒基序可与延伸蛋白B和C结合，并可能将结合蛋白与蛋白酶体降解偶联。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.96.5.2071
Zhang, J G; Farley, A; Nicholson, S E; Willson, T A; Zugaro, L M; Simpson, R J; Moritz, R L; Cary, D; Richardson, R; Hausmann, G; Kile, B T; Kent, S B; Alexander, W S; Metcalf, D; Hilton, D J; Nicola, N A; Baca, M
信号转导
细胞生物学
免疫/内分泌
发表日期：1999
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Mutational analyses of the SOCS proteins suggest a dual domain requirement but distinct mechanisms for inhibition of LIF and IL-6 signal transduction

SOCS蛋白的突变分析表明，抑制LIF和IL-6信号转导需要双结构域，但抑制机制不同。

期刊:EMBO Journal
影响因子:8.3
doi:10.1093/emboj/18.2.375
Nicholson, S E; Willson, T A; Farley, A; Starr, R; Zhang, J G; Baca, M; Alexander, W S; Metcalf, D; Hilton, D J; Nicola, N A
信号转导
LIF
IL-6
发表日期：1999
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Liver degeneration and lymphoid deficiencies in mice lacking suppressor of cytokine signaling-1

缺乏细胞因子信号抑制因子-1的小鼠出现肝脏退化和淋巴细胞缺陷

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.95.24.14395
Starr, R; Metcalf, D; Elefanty, A G; Brysha, M; Willson, T A; Nicola, N A; Hilton, D J; Alexander, W S
信号转导
细胞生物学
免疫/内分泌
发表日期：1998
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Leptin can induce proliferation, differentiation, and functional activation of hemopoietic cells

瘦素可以诱导造血细胞的增殖、分化和功能激活。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.93.25.14564
Gainsford, T; Willson, T A; Metcalf, D; Handman, E; McFarlane, C; Ng, A; Nicola, N A; Alexander, W S; Hilton, D J
细胞生物学
发表日期：1996
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Leukemia inhibitory factor protects against experimental lethal Escherichia coli septic shock in mice

白血病抑制因子可保护小鼠免受实验性致死性大肠杆菌败血性休克的侵害

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.92.5.1337
Waring, P M; Waring, L J; Billington, T; Metcalf, D
白血病
发表日期：1995
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Absence of yolk sac hematopoiesis from mice with a targeted disruption of the scl gene

scl基因靶向破坏的小鼠缺乏卵黄囊造血功能

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.92.15.7075
Robb, L; Lyons, I; Li, R; Hartley, L; Köntgen, F; Harvey, R P; Metcalf, D; Begley, C G
发表日期：1995
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