Metge相关文献与解析，生知库 | 链接生命科学的每一步

Ribosomal RNA Biosynthesis Functionally Programs Tumor-Associated Macrophages to Support Breast Cancer Progression

核糖体RNA生物合成功能性地调控肿瘤相关巨噬细胞，以支持乳腺癌进展

Metge, Brandon J; Williams, Li'an; Swain, Courtney A; Hinshaw, Dominique C; Elhamamsy, Amr R; Chen, Dongquan; Samant, Rajeev S; Shevde, Lalita A

巨噬细胞

Hypoxic stress incites HIF1Î±-driven ribosome biogenesis that can be exploited by targeting RNA Polymerase I.

缺氧应激会引发 HIF1α 驱动的核糖体生物合成，而这种生物合成可以通过靶向 RNA 聚合酶 I 来加以利用

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-025-63315-3

Elhamamsy Amr, Metge Brandon J, Swain Courtney A, Elbahoty Mohamed H, Hinshaw Dominique C, Kammerud Sarah C, Chen Dongquan, Samant Rajeev S, Shevde Lalita A

Nucleolar proteomics identifies S100A16 as a key nucleolar protein driving breast cancer metastasis

核仁蛋白质组学鉴定出S100A16是驱动乳腺癌转移的关键核仁蛋白

期刊:Cell Death & Disease

影响因子:9.6

doi:10.1038/s41419-025-07963-9

Metge, Brandon J; Elbahoty, Mohamed H; Elhamamsy, Amr R; Popple, Anne E; Papineni, Bhavya; Samant, Rajeev S; Shevde, Lalita A

Exploring perceived barriers, facilitators, and team roles in addressing prescribing cascades in primary care teams: Insights from interprofessional focus groups

探讨初级保健团队在应对处方级联问题时所感知到的障碍、促进因素和团队角色：来自跨专业焦点小组的见解

期刊:PLoS One

影响因子:2.6

doi:10.1371/journal.pone.0333829

Toenjes, Sameera; Rodriguez, M Christine; Guilcher, Sara J T; Metge, Colleen; Farrell, Barbara J; Jeffs, Lianne; McCarthy, Lisa M

发表日期：2025

文献求助收藏

De novo neurofibromatosis type 2-related schwannomatosis in a child presenting with intraocular signs as initial manifestations

儿童新发2型神经纤维瘤病相关神经鞘瘤病，以眼内症状为首发表现

期刊:American Journal of Ophthalmology Case Reports

影响因子:

doi:10.1016/j.ajoc.2025.102447

Vienne-Jumeau, Aliénor; Bijon, Jacques; Waintraub, Sacha; Caputo, Georges; Metge, Florence

发表日期：2025

文献求助收藏

"I think of it as planting seeds": challenging patient-provider discussions about COVID-19 vaccination: a qualitative study

“我认为这就像播种”：关于新冠疫苗接种的具有挑战性的患者与医护人员讨论：一项定性研究

期刊:BMC Primary Care

影响因子:

doi:10.1186/s12875-025-03035-1

Driedger, S Michelle; Maier, Ryan; Metge, Colleen; Katz, Alan; Singer, Alex

Targeting EMT using low-dose Teniposide by downregulating ZEB2-driven activation of RNA polymerase I in breast cancer

使用低剂量替尼泊苷通过下调乳腺癌中 ZEB2 驱动的 RNA 聚合酶 I 激活来靶向 EMT

期刊:Cell Death & Disease

影响因子:8.1

doi:10.1038/s41419-024-06694-7

Brandon J Metge, Heba Allah M Alsheikh, Sarah C Kammerud, Dongquan Chen, Devika Das, N Miranda Nebane, J Robert Bostwick, Lalita A Shevde, Rajeev S Samant

The genomic landscape of breast and non-breast cancers from individuals with germline CHEK2 deficiency

携带生殖系CHEK2缺陷个体的乳腺癌和非乳腺癌的基因组图谱

期刊:JNCI Cancer Spectrum

影响因子:4.1

doi:10.1093/jncics/pkae044

Hinić, Snežana; van der Post, Rachel S; Vreede, Lilian; Schuurs-Hoeijmakers, Janneke; Koene, Saskia; Jansen, Erik A M; Bervoets-Metge, Franziska; Mensenkamp, Arjen R; Hoogerbrugge, Nicoline; Ligtenberg, Marjolijn J L; de Voer, Richarda M

A-I-D for cascades: an application of the Behaviour Change Wheel to design a theory-based intervention for addressing prescribing cascades in primary care

针对级联问题的援助：将行为改变轮应用于设计基于理论的干预措施，以解决初级保健中的处方级联问题

期刊:Implementation Science Communications

影响因子:3.3

doi:10.1186/s43058-024-00673-x

McCarthy, Lisa M; Farrell, Barbara J; Metge, Colleen; Jeffs, Lianne; Toenjes, Sameera; Rodriguez, M Christine

发表日期：2024

文献求助收藏

Helping people access benefits: Millions of unclaimed federal dollars are available

帮助人们获得福利：数百万美元的联邦资金无人认领。

Ribosomal RNA Biosynthesis Functionally Programs Tumor-Associated Macrophages to Support Breast Cancer Progression

核糖体RNA生物合成功能性地调控肿瘤相关巨噬细胞，以支持乳腺癌进展

Hypoxic stress incites HIF1Î±-driven ribosome biogenesis that can be exploited by targeting RNA Polymerase I.

缺氧应激会引发 HIF1α 驱动的核糖体生物合成，而这种生物合成可以通过靶向 RNA 聚合酶 I 来加以利用

Nucleolar proteomics identifies S100A16 as a key nucleolar protein driving breast cancer metastasis

核仁蛋白质组学鉴定出S100A16是驱动乳腺癌转移的关键核仁蛋白

Exploring perceived barriers, facilitators, and team roles in addressing prescribing cascades in primary care teams: Insights from interprofessional focus groups

探讨初级保健团队在应对处方级联问题时所感知到的障碍、促进因素和团队角色：来自跨专业焦点小组的见解

De novo neurofibromatosis type 2-related schwannomatosis in a child presenting with intraocular signs as initial manifestations

儿童新发2型神经纤维瘤病相关神经鞘瘤病，以眼内症状为首发表现

"I think of it as planting seeds": challenging patient-provider discussions about COVID-19 vaccination: a qualitative study

“我认为这就像播种”：关于新冠疫苗接种的具有挑战性的患者与医护人员讨论：一项定性研究

Targeting EMT using low-dose Teniposide by downregulating ZEB2-driven activation of RNA polymerase I in breast cancer

使用低剂量替尼泊苷通过下调乳腺癌中 ZEB2 驱动的 RNA 聚合酶 I 激活来靶向 EMT

The genomic landscape of breast and non-breast cancers from individuals with germline CHEK2 deficiency

携带生殖系CHEK2缺陷个体的乳腺癌和非乳腺癌的基因组图谱

A-I-D for cascades: an application of the Behaviour Change Wheel to design a theory-based intervention for addressing prescribing cascades in primary care

针对级联问题的援助：将行为改变轮应用于设计基于理论的干预措施，以解决初级保健中的处方级联问题