日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Disruption of the mRNA m6A writer complex triggers autoimmunity in Arabidopsis.

mRNA m6A写入复合物的破坏会引发拟南芥的自身免疫。

Metheringham Carey L, Srivastava Anjil K, Thorpe Peter, Maji Ankita, Parker Matthew T, Barton Geoffrey J, Simpson Gordon G

U6 snRNA m6A modification is required for accurate and efficient splicing of C. elegans and human pre-mRNAs

U6 snRNA m6A 修饰是秀丽隐杆线虫和人类前 mRNA 准确高效剪接所必需的

Aykut Shen, Katarzyna Hencel, Matthew T Parker, Robyn Scott, Roberta Skukan, Aduragbemi S Adesina, Carey L Metheringham, Eric A Miska, Yunsun Nam, Wilfried Haerty, Gordon G Simpson, Alper Akay

U6 snRNA m6A modification is required for accurate and efficient cis- and trans-splicing of C. elegans mRNAs

U6 snRNA m6A 修饰是准确、高效地进行秀丽隐杆线虫 mRNA 顺式和反式剪接所必需的

Aykut Shen, Katarzyna Hencel, Matthew T Parker, Robyn Scott, Roberta Skukan, Aduragbemi S Adesina, Carey L Metheringham, Eric A Miska, Yunsun Nam, Wilfried Haerty, Gordon G Simpson, Alper Akay

PAD-2-mediated citrullination of nucleophosmin provides an effective target for tumor immunotherapy

PAD-2介导的核磷蛋白瓜氨酸化为肿瘤免疫治疗提供了有效的靶点

Ruhul H Choudhury, Peter Symonds, Samantha J Paston, Ian Daniels, Katherine W Cook, Mohamed Gijon, Rachael L Metheringham, Victoria A Brentville, Lindy G Durrant

Vaccine Can Induce CD4-Mediated Responses to Homocitrullinated Peptides via Multiple HLA-Types and Confer Anti-Tumor Immunity

疫苗可通过多种 HLA 类型诱导 CD4 介导的对同型瓜氨酸肽的反应并产生抗肿瘤免疫力

Katherine Cook, Wei Xue, Suha Atabani, Peter Symonds, Abdullah Al Omari, Ian Daniels, Sabaria Shah, Ruhul Hasan Choudhury, Daisy Weston, Rachael Metheringham, Victoria Brentville, Lindy Durrant

The Clinical and Prognostic Significance of Protein Arginine Deiminases 2 and 4 in Colorectal Cancer

蛋白质精氨酸脱亚氨酶2和4在结直肠癌中的临床和预后意义

Mohamed Gijon, Rachael L Metheringham, Michael S Toss, Samantha J Paston, Lindy G Durrant

Homocitrullination of lysine residues mediated by myeloid-derived suppressor cells in the tumor environment is a target for cancer immunotherapy

肿瘤微环境中髓系来源抑制细胞介导的赖氨酸残基同型瓜氨酸化是癌症免疫治疗的靶点。

Cook, Katherine W; Xue, Wei; Symonds, Peter; Daniels, Ian; Gijon, Mohamed; Boocock, David; Coveney, Clare; Miles, Amanda K; Shah, Sabaria; Atabani, Suha; Choudhury, Ruhul H; Vaghela, Poonam; Weston, Daisy; Metheringham, Rachael L; Brentville, Victoria A; Durrant, Lindy G

Citrullinated Epitopes Identified on Tumour MHC Class II by Peptide Elution Stimulate Both Regulatory and Th1 Responses and Require Careful Selection for Optimal Anti-Tumour Responses

通过肽洗脱鉴定的肿瘤 MHC II 类上的瓜氨酸化表位可刺激调节和 Th1 反应,需要仔细选择才能获得最佳抗肿瘤反应

Peter Symonds, Ana Marcu, Katherine W Cook, Rachael L Metheringham, Lindy G Durrant, Victoria A Brentville

A Novel HAGE/WT1-ImmunoBody® Vaccine Combination Enhances Anti-Tumour Responses When Compared to Either Vaccine Alone

一种新型的HAGE/WT1-ImmunoBody®疫苗组合与单独使用任何一种疫苗相比,都能增强抗肿瘤反应。

Rukaia Almshayakhchi ,Divya Nagarajan ,Jayakumar Vadakekolathu ,Barbara-Ann Guinn ,Stephen Reeder ,Victoria Brentville ,Rachael Metheringham ,A Graham Pockley ,Lindy Durrant ,Stephanie McArdle

Helicase antigen (HAGE)-derived vaccines induce immunity to HAGE and ImmunoBody®-HAGE DNA vaccine delays the growth and metastasis of HAGE-expressing tumors in vivo

解旋酶抗原 (HAGE) 衍生疫苗可诱导对 HAGE 的免疫力,而 ImmunoBody®-HAGE DNA 疫苗可延缓体内表达 HAGE 的肿瘤的生长和转移

Divya Nagarajan, Joshua Pearson, Victoria Brentville, Rachael Metheringham, A Graham Pockley, Lindy Durrant, Stephanie E McArdle