Metko相关文献与解析，生知库 | 链接生命科学的每一步

McMullen, Eric; Joseph, Marissa; Mannala, Samantha; Metko, Dea; Mehta, Shanti; Mar, Kristie; Tarafdar, Nawar; Hwang, Kyobin; Khosravi-Hafshejani, Touraj; Maazi, Mahan; Donovan, Jeffrey

发表日期：2026

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T cell exhaustion in poorly immunogenic HCC is partially rescued by checkpoint blockade but suppressed by oncolytic virotherapy

在免疫原性较差的肝细胞癌中，T细胞耗竭可通过免疫检查点阻断部分挽救，但可通过溶瘤病毒疗法抑制。

期刊:Molecular Therapy

影响因子:12.1

doi:10.1016/j.ymthe.2025.08.046

Thanich Sangsuwannukul ，Benjamin Kendall ，Jason Tonne ，Olivia Liseth ，Jill Thompson ，Kamonlapat Supimon ，Muriel M Metko ，Alex Chen ，Maria P Chiriboga Yerovi ，Rosa Maria Diaz ，Laura Evgin ，Mason J Webb ，Jacob van Vloten ，Satdarshan P Monga ，Sheeba Irshad ，Mark McNiven ，Lewis Roberts ，Richard G Vile

Exploiting viral infection/vaccination to focus high-affinity T cell populations into tumors using oncolytic viro-immunotherapy

利用病毒感染/疫苗接种，通过溶瘤病毒免疫疗法将高亲和力T细胞群定向输送到肿瘤部位。

期刊:Molecular Therapy

影响因子:12.1

doi:10.1016/j.ymthe.2025.08.023

Alexa Veliz Rios,Muriel Metko,Jason Tonne,Jill Thompson,Benjamin Kendall,Alex Chen,Haley Mudrick,David Masopust,Sheeba Irshad,Mary Barry,Michael A Barry,Rosa Maria Diaz,Richard Vile

Subclinical Synovitis Among Patients With Psoriasis Without Musculoskeletal Involvement: A Systematic Review and Meta-Analysis

无肌肉骨骼受累的银屑病患者的亚临床滑膜炎：系统评价和荟萃分析

期刊:Jama Dermatology

影响因子:11

doi:10.1001/jamadermatol.2025.2281

Mehta, Shanti; Xiong, Grace; Metko, Dea; Abdi, Parsa; McMullen, Eric; Alhusayen, Raed

Obesity in Pediatric Hidradenitis Suppurativa: A Scoping Review

儿童化脓性汗腺炎中的肥胖：一项范围综述

期刊:Pediatric Dermatology

影响因子:1.2

doi:10.1111/pde.15746

Mehta, Shanti; Metko, Dea; Lam, Joseph M

Characteristics of Patients With Adult-Onset Dermatomyositis at 2 Tertiary Care Centres in Ontario, Canada

加拿大安大略省两家三级医疗中心成人发病型皮肌炎患者的特征

期刊:

影响因子:

doi:10.1177/12034754241301409

Metko, Dea; Bednar, Dimitra E; Alkhayal, Fares; Pavlova, Viktoria; Legault, Kimberly; Abu-Hilal, Mohannad

发表日期：2025

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Expression of tumor antigens within an oncolytic virus enhances the anti-tumor T cell response

溶瘤病毒内肿瘤抗原的表达可增强抗肿瘤T细胞反应。

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-024-49286-x

Mason J Webb ，Thanich Sangsuwannukul ，Jacob van Vloten ，Laura Evgin ，Benjamin Kendall ，Jason Tonne ，Jill Thompson ，Muriel Metko ，Madelyn Moore ，Maria P Chiriboga Yerovi ，Michael Olin ，Antonella Borgatti ，Mark McNiven ，Satdarshan P S Monga ，Mitesh J Borad ，Alan Melcher ，Lewis R Roberts ，Richard Vile

Subcutaneous white adipose tissue independently regulates burn-induced hypermetabolism via immune-adipose crosstalk

皮下白色脂肪组织通过免疫-脂肪相互作用独立调节烧伤引起的代谢亢进。

期刊:Cell Reports

影响因子:7.5

doi:10.1016/j.celrep.2023.113584

Carly M Knuth ，Dalia Barayan ，Ju Hee Lee ，Christopher Auger ，Lauar de Brito Monteiro ，Zachary Ricciuti ，Dea Metko ，Lisa Wells ，Hoon-Ki Sung ，Robert A Screaton ，Marc G Jeschke

APOBEC3B expression in 293T viral producer cells drives mutations in chimeric antigen receptors and reduces CAR T cell efficacy

293T病毒生产细胞中APOBEC3B的表达驱动嵌合抗原受体发生突变，并降低CAR-T细胞的疗效。

期刊:Molecular Therapy Oncology

影响因子:4.5

doi:10.1016/j.omton.2024.200873

Jack Swanson,Jason Tonne,Thanich Sangsuwannukul,Jill Thompson,Benjamin Kendall,Olivia Liseth,Muriel Metko,Richard Vile

Mutation in pore-helix modulates interplay between filter gate and Ba2+ block in a Kcv channel pore

孔道螺旋的突变调节Kcv通道孔中过滤门和Ba2+阻滞之间的相互作用

期刊:Journal of General Physiology

影响因子:2.9

doi:10.1085/jgp.202313514

Tewes, Noel; Kubitzki, Beatrice; Bytyqi, Flandrit; Metko, Nikola; Mach, Sebastian; Thiel, Gerhard; Rauh, Oliver

发表日期：2024

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Misdiagnoses of Hair and Scalp Disorders in Adult Patients With Skin of Color

有色人种成年患者头发和头皮疾病的误诊

T cell exhaustion in poorly immunogenic HCC is partially rescued by checkpoint blockade but suppressed by oncolytic virotherapy

在免疫原性较差的肝细胞癌中，T细胞耗竭可通过免疫检查点阻断部分挽救，但可通过溶瘤病毒疗法抑制。

Exploiting viral infection/vaccination to focus high-affinity T cell populations into tumors using oncolytic viro-immunotherapy

利用病毒感染/疫苗接种，通过溶瘤病毒免疫疗法将高亲和力T细胞群定向输送到肿瘤部位。

Subclinical Synovitis Among Patients With Psoriasis Without Musculoskeletal Involvement: A Systematic Review and Meta-Analysis

无肌肉骨骼受累的银屑病患者的亚临床滑膜炎：系统评价和荟萃分析

Obesity in Pediatric Hidradenitis Suppurativa: A Scoping Review

儿童化脓性汗腺炎中的肥胖：一项范围综述

Characteristics of Patients With Adult-Onset Dermatomyositis at 2 Tertiary Care Centres in Ontario, Canada

加拿大安大略省两家三级医疗中心成人发病型皮肌炎患者的特征

Expression of tumor antigens within an oncolytic virus enhances the anti-tumor T cell response

溶瘤病毒内肿瘤抗原的表达可增强抗肿瘤T细胞反应。

Subcutaneous white adipose tissue independently regulates burn-induced hypermetabolism via immune-adipose crosstalk

皮下白色脂肪组织通过免疫-脂肪相互作用独立调节烧伤引起的代谢亢进。

APOBEC3B expression in 293T viral producer cells drives mutations in chimeric antigen receptors and reduces CAR T cell efficacy

293T病毒生产细胞中APOBEC3B的表达驱动嵌合抗原受体发生突变，并降低CAR-T细胞的疗效。

Mutation in pore-helix modulates interplay between filter gate and Ba2+ block in a Kcv channel pore

孔道螺旋的突变调节Kcv通道孔中过滤门和Ba2+阻滞之间的相互作用