日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Correction to "Design of Tau Aggregation Inhibitors Using Iterative Machine Learning and a Polymorph-Specific Brain-Seeded Fibril Amplification Assay"

对“利用迭代机器学习和多晶型特异性脑种子纤维扩增分析设计Tau蛋白聚集抑制剂”一文的更正

期刊:Journal of the American Chemical Society
影响因子:15.6
doi:10.1021/jacs.5c18723
Santambrogio, Alessia; Horne, Robert I; Metrick, Michael A 2nd; Gallagher, Nicholas C T; Brotzakis, Z Faidon; Rinauro, Dillon; Vourkou, Ergina; Papanikolopoulou, Katerina; Skoulakis, Efthimios M C; Linse, Sara; Caughey, Byron; Vendruscolo, Michele
神经科学
发表日期：2026
文献求助 收藏

Classification of tauopathies from human brain homogenates through salt-modulated tau amplification

通过盐调节的tau蛋白扩增对人脑匀浆中的tau蛋白病进行分类

期刊:Alzheimers & Dementia
影响因子:11.1
doi:10.1002/alz.71112
Santambrogio, Alessia; Metrick, Michael A 2nd; Xu, Peifeng; Gallagher, Nicholas C T; Koga, Shunsuke; Ghetti, Bernardino; Dickson, Dennis W; Caughey, Byron; Vendruscolo, Michele
神经科学
发表日期：2026
文献求助 收藏

Tracking tau and cellular responses in human iPSC-microglia: from uptake to seedable secretion, including in extracellular vesicles

追踪人类iPSC-小胶质细胞中的tau蛋白和细胞反应：从摄取到可播种分泌，包括在细胞外囊泡中

期刊:Alzheimers & Dementia
影响因子:11.1
doi:10.1002/alz.71337
Karabova, Maria Kreger; Del Ser-Badia, Anna; Hedegaard, Anne; Washer, Sam J; Baykam, Zeynep; O'Brien, Darragh P; Vendrell, Iolanda; Hester, Svenja S; Fischer, Roman; Johnson, Errin; Melia, Charlotte E; Matthews-Palmer, Teige R S; Matadeen, Rishi; Santambrogio, Alessia; Metrick, Michael A 2nd; Vendruscolo, Michele; Keeling, Sophie; Cheam, Kimberly Ai Xian; McEwan, William A; Kosik, Kenneth S; Day, Theresa A; James, William S; Cowley, Sally A
胶质细胞
囊泡
细胞生物学
发表日期：2026
文献求助 收藏

Design of Tau Aggregation Inhibitors Using Iterative Machine Learning and a Polymorph-Specific Brain-Seeded Fibril Amplification Assay

利用迭代机器学习和多晶型特异性脑种子纤维扩增试验设计Tau蛋白聚集抑制剂

期刊:Journal of the American Chemical Society
影响因子:15.6
doi:10.1021/jacs.5c12812
Santambrogio, Alessia; Horne, Robert I; Metrick, Michael A 2nd; Gallagher, Nicholas C T; Brotzakis, Z Faidon; Rinauro, Dillon; Vourkou, Ergina; Papanikolopoulou, Katerina; Skoulakis, Efthimios M C; Linse, Sara; Caughey, Byron; Vendruscolo, Michele
神经科学
发表日期：2025
文献求助 收藏

Serial amplification of tau filaments using Alzheimer's brain homogenates and C322A or C322S recombinant tau

利用阿尔茨海默病脑匀浆和C322A或C322S重组tau蛋白进行tau蛋白丝的连续扩增

期刊:FEBS Letters
影响因子:3
doi:10.1002/1873-3468.70141
Santambrogio, Alessia; Lövestam, Sofia; Metrick, Michael A 2nd; Löhr, Thomas; Xu, Peifeng; Gallagher, Nicholas C T; Ghetti, Bernardino; Caughey, Byron; Scheres, Sjors H W; Vendruscolo, Michele
阿尔茨海默症
神经科学
发表日期：2025
文献求助 收藏

Discovery and Preclinical Characterization of BIIB129, a Covalent, Selective, and Brain-Penetrant BTK Inhibitor for the Treatment of Multiple Sclerosis

BIIB129 的发现和临床前表征：一种共价、选择性且能穿透血脑屏障的 BTK 抑制剂，用于治疗多发性硬化症

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.4c00220
Himmelbauer, Martin K; Bajrami, Bekim; Basile, Rebecca; Capacci, Andrew; Chen, TeYu; Choi, Colin K; Gilfillan, Rab; Gonzalez-Lopez de Turiso, Felix; Gu, Chungang; Hoemberger, Marc; Johnson, Douglas S; Jones, J Howard; Kadakia, Ekta; Kirkland, Melissa; Lin, Edward Y; Liu, Ying; Ma, Bin; Magee, Tom; Mantena, Srinivasa; Marx, Isaac E; Metrick, Claire M; Mingueneau, Michael; Murugan, Paramasivam; Muste, Cathy A; Nadella, Prasad; Nevalainen, Marta; Parker Harp, Chelsea R; Pattaropong, Vatee; Pietrasiewicz, Alicia; Prince, Robin J; Purgett, Thomas J; Santoro, Joseph C; Schulz, Jurgen; Sciabola, Simone; Tang, Hao; Vandeveer, H George; Wang, Ti; Yousaf, Zain; Helal, Christopher J; Hopkins, Brian T
血脑屏障
BTK
神经科学
多发性硬化症
发表日期：2024
文献求助 收藏

Group prenatal care successes, challenges, and frameworks for scaling up: a case study in adopting health care innovations

团体产前保健的成功经验、挑战及推广框架：以医疗保健创新应用为例

期刊:Implementation Science Communications
影响因子:3.3
doi:10.1186/s43058-024-00556-1
Masters, Claire; Carandang, Rogie Royce; Lewis, Jessica B; Hagaman, Ashley; Metrick, Rebecca; Ickovics, Jeannette R; Cunningham, Shayna D
发表日期：2024
文献求助 收藏

Case report of a patient with unclassified tauopathy with molecular and neuropathological features of both progressive supranuclear palsy and corticobasal degeneration

病例报告：一名未分类的 tau 蛋白病患者，其分子和神经病理学特征为进行性核上性麻痹和皮质基底节变性

期刊:Acta Neuropathologica Communications
影响因子:6.2
doi:10.1186/s40478-023-01584-z
Shunsuke Koga, Michael A Metrick 2nd, Lawrence I Golbe, Alessia Santambrogio, Minji Kim, Alexandra I Soto-Beasley, Ronald L Walton, Matthew C Baker, Cristhoper Fernandez De Castro, Michael DeTure, David Russell, Bradford A Navia, Christine Sandiego, Owen A Ross, Michele Vendruscolo, Byron Caughey, D
神经
发表日期：2023
文献求助 收藏

Computational maturation of a single-domain antibody against Aβ42 aggregation

针对Aβ42聚集的单域抗体的计算成熟

期刊:Chemical Science
影响因子:7.4
doi:10.1039/d1sc03898b
Lin, Jiacheng; Figazzolo, Chiara; Metrick, Michael A 2nd; Sormanni, Pietro; Vendruscolo, Michele
发表日期：2021
文献求助 收藏

Detection of chronic wasting disease in mule and white-tailed deer by RT-QuIC analysis of outer ear

利用RT-QuIC分析外耳组织检测骡鹿和白尾鹿的慢性消耗性疾病

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-021-87295-8
Ferreira, Natalia C; Charco, Jorge M; Plagenz, Jakob; Orru, Christina D; Denkers, Nathanial D; Metrick, Michael A 2nd; Hughson, Andrew G; Griffin, Karen A; Race, Brent; Hoover, Edward A; Castilla, Joaquín; Nichols, Tracy A; Miller, Michael W; Caughey, Byron
发表日期：2021
文献求助 收藏