日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Synthetic bottlebrush block copolymer prevents disease onset in Duchenne muscular dystrophy

合成瓶刷状嵌段共聚物可预防杜氏肌营养不良症的发病

Cohen, Houda; Angulski, Addeli Bez Batti; Quick, Joseph D; Kuebler, Taylor S; Thompson, Brian R; Bauer, John; Hahn, Dongwoo; Townsend, DeWayne; Hassler, Joseph F; Hackel, Benjamin J; Lodge, Timothy P; Sham, Yuk Y; Bates, Frank S; Metzger, Joseph M

Isotopic Labeling-Enabled Chemical Proteomics Analysis Revealed Structural and Functional Features of Allysine Modifications in Mammalian Cells and Tissues

同位素标记化学蛋白质组学分析揭示了哺乳动物细胞和组织中赖氨酸修饰的结构和功能特征

Sin, Yi-Cheng; Hosny, Nora; Batti Angulski, Addeli Bez; Kim, Do-Hyung; Metzger, Joseph M; Chen, Yue

Biaxial length-tension relationship in single cardiac myocytes.

单个心肌细胞的双轴长度-张力关系

Rothermel Taylor M, Cohen Houda, Grosberg Anna, Metzger Joseph M, Alford Patrick W

Elucidating cancer cachexia-mediated aberrant cardiac wasting signaling in human iPSC-derived cardiac muscle

阐明癌症恶病质介导的人类iPSC来源心肌异常萎缩信号通路

Hosny, Nora; Cohen, Houda; Elafany, Mohamed Waleed; Schreifels, Jeff; Bauer, John; Gulati, Rishi; Thompson, Brian R; Liu, Julia C; Metzger, Joseph M

Gene transfer of human cardiomyopathy β-MyHC mutant R403Q directly alters intact cardiac myocyte calcium homeostasis and causes hyper-contractility

人类心肌病β-MyHC突变体R403Q的基因转移可直接改变完整心肌细胞的钙稳态,并导致心肌过度收缩。

Herron, Todd J; Devaney, Eric; Guerrero-Serna, Guadalupe; Mundada, Lakshmi; Metzger, Joseph M

Duchenne muscular dystrophy: disease mechanism and therapeutic strategies

杜氏肌营养不良症:疾病机制和治疗策略

Bez Batti Angulski, Addeli; Hosny, Nora; Cohen, Houda; Martin, Ashley A; Hahn, Dongwoo; Bauer, Jack; Metzger, Joseph M

Cardiac Sarcomere Signaling in Health and Disease

心脏肌节信号传导在健康和疾病中的作用

Martin, Ashley A; Thompson, Brian R; Hahn, Dongwoo; Angulski, Addeli Bez Batti; Hosny, Nora; Cohen, Houda; Metzger, Joseph M

The road to physiological maturation of stem cell-derived cardiac muscle runs through the sarcomere

干细胞衍生的心肌细胞走向生理成熟的道路要经过肌节。

Metzger, Joseph M

Cardiac myocyte intrinsic contractility and calcium handling deficits underlie heart organ dysfunction in murine cancer cachexia

心肌细胞固有收缩力和钙处理缺陷是小鼠癌症恶病质中心脏器官功能障碍的根本原因。

Law, Michelle L; Metzger, Joseph M

Sarcomere integrated biosensor detects myofilament-activating ligands in real time during twitch contractions in live cardiac muscle.

肌节集成生物传感器可在活体心肌抽搐收缩期间实时检测肌丝激活配体

Vetter Anthony D, Martin Ashley A, Thompson Brian R, Thomas David D, Metzger Joseph M