p21(+)TREM2(+) senescent macrophages fuel inflammaging and metabolic dysfunction-associated steatotic liver disease
p21(+)TREM2(+)衰老巨噬细胞促进炎症衰老和代谢功能障碍相关的脂肪肝疾病。
期刊:Nature Aging
影响因子:19.4
doi:10.1038/s43587-026-01101-6
Salladay-Perez, Ivan A; Avila, Itzetl; Estrada, Lizeth; Alexandru, Andreea C; Ponce, Cristian; Dhingra, Anika; Torres, Grasiela; Deng, Christina Y; Hegde, Ronak; Gensheimer, Julia; Kale, Abhijit; Heckenbach, Indra; Hui, Simon; Edillor, Chantle; Soto, Jose A; Napior, Alexander J; Little, Isaiah; Larsen, Mark; Rose, Jacob; Farahi, Lia; Lopez Gonzalez, Edwin D J; Krieger, Matthew R; Chowdhury, Kushan; Sharma, Mridul; Jiang, Yuming; Williams, Kevin; Scheibye-Knudsen, Morten; Koehler, Carla M; Meyer, Jesse G; Mack, Julia J; Brenner, Charles; Bensinger, Steven J; Lagger, Cyril; de Magalhães, João Pedro; Schilling, Birgit; Singh, Rajat; Verdin, Eric; Lusis, Aldons J; Covarrubias, Anthony J
巨噬细胞
炎症
炎症/感染
巨噬细胞
TREM2
代谢
脂肪肝
衰老
细胞生物学
免疫/内分泌
