PARP11 inhibition inactivates tumor-infiltrating regulatory T cells and improves the efficacy of immunotherapies
PARP11抑制剂可使肿瘤浸润性调节性T细胞失活,并提高免疫疗法的疗效。
期刊:Cell Reports Medicine
影响因子:11.7
doi:10.1016/j.xcrm.2024.101649
Raghavendra Basavaraja,Hongru Zhang,Ágnes Holczbauer,Zhen Lu,Enrico Radaelli,Charles-Antoine Assenmacher,Subin S George,Vamshidhar C Nallamala,Daniel P Beiting,Mirella L Meyer-Ficca,Ralph G Meyer,Wei Guo,Yi Fan,Andrew J Modzelewski,Vladimir S Spiegelman,Michael S Cohen,Serge Y Fuchs
细胞生物学
肿瘤
免疫/内分泌
T细胞
PARP1
PARP
T细胞