Safety and tolerability of HIV-1 multiantigen pDNA vaccine given with IL-12 plasmid DNA via electroporation, boosted with a recombinant vesicular stomatitis virus HIV Gag vaccine in healthy volunteers in a randomized, controlled clinical trial
在一项随机对照临床试验中,评估了通过电穿孔法接种含IL-12质粒DNA的HIV-1多抗原pDNA疫苗,并用重组水疱性口炎病毒HIV Gag疫苗加强免疫后,健康志愿者的安全性和耐受性。
期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0202753
Elizaga, Marnie L; Li, Shuying S; Kochar, Nidhi K; Wilson, Gregory J; Allen, Mary A; Tieu, Hong Van N; Frank, Ian; Sobieszczyk, Magdalena E; Cohen, Kristen W; Sanchez, Brittany; Latham, Theresa E; Clarke, David K; Egan, Michael A; Eldridge, John H; Hannaman, Drew; Xu, Rong; Ota-Setlik, Ayuko; McElrath, M Juliana; Hay, Christine Mhorag