Chemotherapy-induced macrophage CXCL7 expression drives tumor chemoresistance via the STAT1/PHGDH-serine metabolism axis and SAM paracrine feedback to M2 polarization.
化疗诱导的巨噬细胞 CXCL7 表达通过 STAT1/PHGDH-丝氨酸代谢轴和 SAM 旁分泌反馈驱动肿瘤对 M2 极化的耐药性
期刊:Cell Death & Disease
影响因子:9.6
doi:10.1038/s41419-025-07712-y
Liu Shuguang, Gong Hui, Li Peihang, Hu Jiahao, Li Yixuan, Xu Rou, Cai Junchao, Wang Shuqi, Cai Jiayi, Ma Hongmei, Mi Xirong, Li Yifan, Zhou Qingbo, Zhou Qiming, Yang Weiqiang, Li Riqing, Song Libing, Fang Lishan
