Michael Andreeff相关文献与解析，生知库 | 链接生命科学的每一步

Bing Z Carter ，Po Yee Mak ，Edward Ayoub ，Xiaogang Wu ，Baozhen Ke ，Yuki Nishida ，Andrew Futreal ，Lauren B Ostermann ，Andrea D Bedoy ，Steffen Boettcher ，Courtney D DiNardo ，Anna Puzio-Kuter ，Masha V Poyurovsky ，Arnold Levine ，Michael Andreeff

P53

白血病

发表日期：2025

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GD3 synthase drives resistance to p53-induced apoptosis in breast cancer by modulating mitochondrial function

GD3合成酶通过调节线粒体功能驱动乳腺癌细胞对p53诱导的细胞凋亡产生抵抗力。

期刊:Oncogene

影响因子:6.9

doi:10.1038/s41388-025-03432-x

Vivek Anand ，Fouad El-Dana ，Natalia Baran ，Jenny Borgman ，Zheng Yin ，Hong Zhao ，Stephen T Wong ，Michael Andreeff ，V Lokesh Battula

Targeting GD2 with naxitamab overcomes GD3 synthase-driven immune suppression in triple-negative breast cancer

使用纳西他单抗靶向GD2可克服三阴性乳腺癌中GD3合成酶驱动的免疫抑制

期刊:NPJ Breast Cancer

影响因子:6.5

doi:10.1038/s41523-025-00843-7

Vivek Anand # ，Bolutyfe Oderinde # ，Maryam Siddiqui ，Anudishi Tyagi ，Jenny Borgman ，Chong Wu ，Michael Andreeff ，V Lokesh Battula

PPARγ-induced upregulation of fatty acid metabolism confers resistance to venetoclax and decitabine therapy in AML

PPARγ诱导的脂肪酸代谢上调赋予急性髓系白血病（AML）对维奈托克和地西他滨治疗的耐药性。

期刊:

影响因子:

doi:10.1016/j.bneo.2025.100121.

Kotoko Yamatani ,Tatsuro Watanabe ,Kaori Saito ,Abdullah Khasawneh ,Abhishek Maiti ,Zhihong Zeng ,Kala Hayes ,Shinya Kimura ,Courtney D DiNardo ,Xiaoping Su ,Shuko Nojiri ,Yasushi Okazaki ,Michael Andreeff ,Marina Konopleva ,Yoko Tabe

Mitochondrial regulation of GPX4 inhibition-mediated ferroptosis in acute myeloid leukemia

线粒体对急性髓系白血病中 GPX4 抑制介导的铁死亡的调节

期刊:Leukemia

影响因子:12.8

doi:10.1038/s41375-023-02117-2

Hiroki Akiyama, Ran Zhao, Lauren B Ostermann, Ziyi Li, Matthew Tcheng, Samar J Yazdani, Arman Moayed, Malcolm L Pryor 2nd, Sandeep Slngh, Natalia Baran, Edward Ayoub, Yuki Nishida, Po Yee Mak, Vivian R Ruvolo, Bing Z Carter, Aaron D Schimmer, Michael Andreeff, Jo Ishizawa

Age-specific induction of mutant p53 drives clonal hematopoiesis and acute myeloid leukemia in adult mice

成年小鼠中突变型p53的年龄特异性诱导驱动克隆性造血和急性髓系白血病

期刊:Cell Reports Medicine

影响因子:11.7

doi:10.1016/j.xcrm.2024.101558

Rasoul Pourebrahim ，Rafael Heinz Montoya ，Hiroki Akiyama ，Lauren Ostermann ，Shayuan Khazaei ，Muharrem Muftuoglu ，Natalia Baran ，Ran Zhao ，Tom Lesluyes ，Bin Liu ，Joseph D Khoury ，Mihai Gagea ，Peter Van Loo ，Michael Andreeff

白血病

发表日期：2024

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Protocol for monitoring clonal hematopoiesis in transgenic mouse models using multispectral imaging

使用多光谱成像监测转基因小鼠模型中的克隆造血的方案

期刊:STAR Protocols

影响因子:1.3

doi:10.1016/j.xpro.2024.103362

Priyanka Khanna, Lauren B Ostermann, Shayaun Khazaei, Ran Zhao, Michael Andreeff, Rasoul Pourebrahim

FlowCytometry

发表日期：2024

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ABCC1 and glutathione metabolism limit the efficacy of BCL-2 inhibitors in acute myeloid leukemia

ABCC1 和谷胱甘肽代谢限制了 BCL-2 抑制剂对急性髓系白血病的疗效

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-023-41229-2

Jessica Ebner #, Johannes Schmoellerl #, Martin Piontek, Gabriele Manhart, Selina Troester, Bing Z Carter, Heidi Neubauer, Richard Moriggl, Gergely Szakács, Johannes Zuber, Thomas Köcher, Michael Andreeff, Wolfgang R Sperr, Peter Valent, Florian Grebien

Combined inhibition of BCL-2 and MCL-1 overcomes BAX deficiency-mediated resistance of TP53-mutant acute myeloid leukemia to individual BH3 mimetics

联合抑制 BCL-2 和 MCL-1 可克服 BAX 缺陷介导的 TP53 突变型急性髓系白血病对单一 BH3 模拟物的耐药性。

期刊:Blood Cancer Journal

影响因子:12.9

doi:10.1038/s41408-023-00830-w

Bing Z Carter ，Po Yee Mak ，Wenjing Tao ，Edward Ayoub ，Lauren B Ostermann ，Xuelin Huang ，Sanam Loghavi ，Steffen Boettcher ，Yuki Nishida ，Vivian Ruvolo ，Paul E Hughes ，Phuong K Morrow ，Torsten Haferlach ，Steven Kornblau ，Muharrem Muftuoglu ，Michael Andreeff

FLT3 inhibitors upregulate CXCR4 and E-selectin ligands via ERK suppression in AML cells and CXCR4/E-selectin inhibition enhances anti-leukemia efficacy of FLT3-targeted therapy in AML

FLT3 抑制剂通过抑制 AML 细胞中的 ERK 来上调 CXCR4 和 E-选择素配体，而 CXCR4/E-选择素抑制可增强 FLT3 靶向治疗对 AML 的抗白血病疗效

期刊:Leukemia

影响因子:12.8

doi:10.1038/s41375-023-01897-x

Yannan Jia #, Weiguo Zhang #, Mahesh Basyal, Kyung Hee Chang, Lauren Ostermann, Jared K Burks, Charlie Ly, Hong Mu-Mosley, Qi Zhang, Xin Han, William E Fogler, John L Magnani, Arnaud Lesegretain, Anna A Zal, Tomasz Zal, Michael Andreeff

Restoring p53 wild-type conformation in TP53-Y220C-mutant acute myeloid leukemia

恢复TP53-Y220C突变型急性髓系白血病中p53野生型构象

GD3 synthase drives resistance to p53-induced apoptosis in breast cancer by modulating mitochondrial function

GD3合成酶通过调节线粒体功能驱动乳腺癌细胞对p53诱导的细胞凋亡产生抵抗力。

Targeting GD2 with naxitamab overcomes GD3 synthase-driven immune suppression in triple-negative breast cancer

使用纳西他单抗靶向GD2可克服三阴性乳腺癌中GD3合成酶驱动的免疫抑制

PPARγ-induced upregulation of fatty acid metabolism confers resistance to venetoclax and decitabine therapy in AML

PPARγ诱导的脂肪酸代谢上调赋予急性髓系白血病（AML）对维奈托克和地西他滨治疗的耐药性。

Mitochondrial regulation of GPX4 inhibition-mediated ferroptosis in acute myeloid leukemia

线粒体对急性髓系白血病中 GPX4 抑制介导的铁死亡的调节

Age-specific induction of mutant p53 drives clonal hematopoiesis and acute myeloid leukemia in adult mice

成年小鼠中突变型p53的年龄特异性诱导驱动克隆性造血和急性髓系白血病

Protocol for monitoring clonal hematopoiesis in transgenic mouse models using multispectral imaging

使用多光谱成像监测转基因小鼠模型中的克隆造血的方案

ABCC1 and glutathione metabolism limit the efficacy of BCL-2 inhibitors in acute myeloid leukemia

ABCC1 和谷胱甘肽代谢限制了 BCL-2 抑制剂对急性髓系白血病的疗效

Combined inhibition of BCL-2 and MCL-1 overcomes BAX deficiency-mediated resistance of TP53-mutant acute myeloid leukemia to individual BH3 mimetics

联合抑制 BCL-2 和 MCL-1 可克服 BAX 缺陷介导的 TP53 突变型急性髓系白血病对单一 BH3 模拟物的耐药性。

FLT3 inhibitors upregulate CXCR4 and E-selectin ligands via ERK suppression in AML cells and CXCR4/E-selectin inhibition enhances anti-leukemia efficacy of FLT3-targeted therapy in AML

FLT3 抑制剂通过抑制 AML 细胞中的 ERK 来上调 CXCR4 和 E-选择素配体，而 CXCR4/E-选择素抑制可增强 FLT3 靶向治疗对 AML 的抗白血病疗效