日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

IL-22 promotes mucin-type O-glycosylation and MATH1+ cell-mediated amelioration of intestinal inflammation

IL-22促进黏蛋白型O-糖基化和MATH1+细胞介导的肠道炎症缓解

Ankita Singh ,Michael Beaupre ,Cecilia Villegas-Novoa ,Kiyoshi Shiomitsu ,Stephen J Gaudino ,Suzanne Tawch ,Ruhee Damle ,Cody Kempen ,Biswa Choudhury ,Jeremy P McAleer ,Brian S Sheridan ,Paula Denoya ,Richard S Blumberg ,Patrick Hearing ,Nancy L Allbritton ,Pawan Kumar

IL-17RA-signaling in Lgr5+ intestinal stem cells induces expression of transcription factor ATOH1 to promote secretory cell lineage commitment

IL-17RA信号通路在Lgr5+肠道干细胞中诱导转录因子ATOH1的表达,从而促进分泌细胞谱系分化。

Xun Lin ,Stephen J Gaudino ,Kyung Ku Jang ,Tej Bahadur ,Ankita Singh ,Anirban Banerjee ,Michael Beaupre ,Timothy Chu ,Hoi Tong Wong ,Chang-Kyung Kim ,Cody Kempen ,Jordan Axelrad ,Huakang Huang ,Saba Khalid ,Vyom Shah ,Onur Eskiocak ,Olivia B Parks ,Artan Berisha ,Jeremy P McAleer ,Misty Good ,Miko Hoshino ,Richard Blumberg ,Agnieszka B Bialkowska ,Sarah L Gaffen ,Jay K Kolls ,Vincent W Yang ,Semir Beyaz ,Ken Cadwell ,Pawan Kumar

IL-22 receptor signaling in Paneth cells is critical for their maturation, microbiota colonization, Th17-related immune responses, and anti-Salmonella immunity

潘氏细胞中的IL-22受体信号传导对其成熟、微生物群定植、Th17相关免疫反应以及抗沙门氏菌免疫至关重要。

Stephen J Gaudino ,Michael Beaupre ,Xun Lin ,Preet Joshi ,Sonika Rathi ,Patrick A McLaughlin ,Cody Kempen ,Neil Mehta ,Onur Eskiocak ,Brian Yueh ,Richard S Blumberg ,Adrianus W M van der Velden ,Kenneth R Shroyer ,Agnieszka B Bialkowska ,Semir Beyaz ,Pawan Kumar