日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Klebsiella pneumoniae hijacks the Toll-IL-1R protein SARM1 in a type I IFN-dependent manner to antagonize host immunity

肺炎克雷伯菌以I型干扰素依赖的方式劫持Toll-IL-1R蛋白SARM1,从而拮抗宿主免疫。

Claudia Feriotti ,Joana Sá-Pessoa ,Ricardo Calderón-González ,Lili Gu ,Brenda Morris ,Ryoichi Sugisawa ,Jose L Insua ,Michael Carty ,Amy Dumigan ,Rebecca J Ingram ,Adrien Kissenpfening ,Andrew G Bowie ,José A Bengoechea

SARM1 Promotes Photoreceptor Degeneration in an Oxidative Stress Model of Retinal Degeneration

SARM1 在视网膜变性的氧化应激模型中促进光感受器变性

Luke Gibbons, Ema Ozaki, Chris Greene, Anne Trappe, Michael Carty, Judith A Coppinger, Andrew G Bowie, Matthew Campbell, Sarah L Doyle

SARM1 Ablation Is Protective and Preserves Spatial Vision in an In Vivo Mouse Model of Retinal Ganglion Cell Degeneration

SARM1 消融对视网膜神经节细胞变性的活体小鼠模型具有保护作用并可保留空间视觉

Laura K Finnegan, Naomi Chadderton, Paul F Kenna, Arpad Palfi, Michael Carty, Andrew G Bowie, Sophia Millington-Ward, G Jane Farrar

CRISPR/Cas9-mediated SARM1 knockout and epitope-tagged mice reveal that SARM1 does not regulate nuclear transcription, but is expressed in macrophages

CRISPR/Cas9 介导的 SARM1 敲除和表位标记小鼠表明,SARM1 不调节核转录,但在巨噬细胞中表达

Ciara G Doran, Ryoichi Sugisawa, Michael Carty, Fiona Roche, Claire Fergus, Karsten Hokamp, Vincent P Kelly, Andrew G Bowie

SARM1 deficiency promotes rod and cone photoreceptor cell survival in a model of retinal degeneration

SARM1 缺乏可促进视网膜变性模型中的视杆细胞和视锥细胞存活

Ema Ozaki, Luke Gibbons, Nuno Gb Neto, Paul Kenna, Michael Carty, Marian Humphries, Pete Humphries, Matthew Campbell, Michael Monaghan, Andrew Bowie, Sarah L Doyle

Cell Survival and Cytokine Release after Inflammasome Activation Is Regulated by the Toll-IL-1R Protein SARM

炎症小体激活后细胞存活和细胞因子释放受 Toll-IL-1R 蛋白 SARM 调控

Michael Carty, Jay Kearney, Katharine A Shanahan, Emily Hams, Ryoichi Sugisawa, Dympna Connolly, Ciara G Doran, Natalia Muñoz-Wolf, Claudia Gürtler, Katherine A Fitzgerald, Ed C Lavelle, Padraic G Fallon, Andrew G Bowie

Poxviral protein E3-altered cytokine production reveals that DExD/H-box helicase 9 controls Toll-like receptor-stimulated immune responses

痘病毒蛋白 E3 改变的细胞因子产生表明 DExD/H-box 解旋酶 9 控制 Toll 样受体刺激的免疫反应

Alan Dempsey, Sinead E Keating, Michael Carty, Andrew G Bowie

Alum Activates the Bovine NLRP3 Inflammasome

明矾激活牛 NLRP3 炎症小体

Ciaran Harte, Aoife L Gorman, S McCluskey, Michael Carty, Andrew G Bowie, C J Scott, Kieran G Meade, Ed C Lavelle

SARM regulates CCL5 production in macrophages by promoting the recruitment of transcription factors and RNA polymerase II to the Ccl5 promoter

SARM 通过促进转录因子和 RNA 聚合酶 II 募集到 Ccl5 启动子来调节巨噬细胞中的 CCL5 产生

Claudia Gürtler, Michael Carty, Jay Kearney, Stefan A Schattgen, Aihao Ding, Katherine A Fitzgerald, Andrew G Bowie