Phosphorylation and stabilization of EZH2 by DCAF1/VprBP trigger aberrant gene silencing in colon cancer
DCAF1/VprBP介导的EZH2磷酸化和稳定作用可触发结肠癌中的异常基因沉默。
期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-023-37883-1
Nikhil B Ghate # ,Sungmin Kim # ,Yonghwan Shin ,Jinman Kim ,Michael Doche ,Scott Valena ,Alan Situ ,Sangnam Kim ,Suhn K Rhie ,Heinz-Josef Lenz ,Tobias S Ulmer ,Shannon M Mumenthaler ,Woojin An
EZH2
信号转导
肿瘤
DCAF1
磷酸化
肠癌
肿瘤免疫
表观遗传
