A Large Panel of Isogenic APP and PSEN1 Mutant Human iPSC Neurons Reveals Shared Endosomal Abnormalities Mediated by APP β-CTFs, Not Aβ
大量同源 APP 和 PSEN1 突变人类 iPSC 神经元揭示出由 APP β-CTF 而非 Aβ 介导的共同内体异常
期刊:Neuron
影响因子:14.7
doi:10.1016/j.neuron.2019.07.010
Dylan Kwart, Andrew Gregg, Claudia Scheckel, Elisabeth A Murphy, Dominik Paquet, Michael Duffield, John Fak, Olav Olsen, Robert B Darnell, Marc Tessier-Lavigne
