Discovery of 5-chloro-N2-[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]-N4-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine (AZD1480) as a novel inhibitor of the Jak/Stat pathway
发现 5-氯-N2-[(1S)-1-(5-氟嘧啶-2-基)乙基]-N4-(5-甲基-1H-吡唑-3-基)嘧啶-2,4-二胺 (AZD1480) 作为 Jak/Stat 通路的新型抑制剂
期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/jm1011319
Stephanos Ioannidis, Michelle L Lamb, Tao Wang, Lynsie Almeida, Michael H Block, Audrey M Davies, Bo Peng, Mei Su, Hai-Jun Zhang, Ethan Hoffmann, Caroline Rivard, Isabelle Green, Tina Howard, Hannah Pollard, Jon Read, Marat Alimzhanov, Geraldine Bebernitz, Kirsten Bell, Minwei Ye, Dennis Huszar, Mic
