日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Interneuronal In Vivo Transfer of Synaptic Proteins

突触蛋白的神经元间体内转移

Michael Klinkenberg, Michael Helwig, Rita Pinto-Costa, Angela Rollar, Raffaella Rusconi, Donato A Di Monte, Ayse Ulusoy

Neuronal hyperactivity-induced oxidant stress promotes in vivo α-synuclein brain spreading

神经元过度活跃引起的氧化应激促进体内 α-突触核蛋白脑扩散

Michael Helwig, Ayse Ulusoy, Angela Rollar, Sinead A O'Sullivan, Shirley S L Lee, Helia Aboutalebi, Rita Pinto-Costa, Benjamin Jevans, Michael Klinkenberg, Donato A Di Monte

The proSAAS Chaperone Provides Neuroprotection and Attenuates Transsynaptic α-Synuclein Spread in Rodent Models of Parkinson's Disease

proSAAS 分子伴侣在帕金森病啮齿动物模型中提供神经保护并减弱跨突触 α-突触核蛋白扩散

Iris Lindberg, Zhan Shu, Hoa Lam, Michael Helwig, Nur Yucer, Alexander Laperle, Clive N Svendsen, Donato A Di Monte, Nigel T Maidment

Brain-to-stomach transfer of α-synuclein via vagal preganglionic projections

α-突触核蛋白通过迷走神经节前投射从脑到胃的转移

Ayse Ulusoy, Robert J Phillips, Michael Helwig, Michael Klinkenberg, Terry L Powley, Donato A Di Monte

Brain propagation of transduced α-synuclein involves non-fibrillar protein species and is enhanced in α-synuclein null mice

转导的 α-突触核蛋白在脑内的传播涉及非纤维蛋白种类,并且在 α-突触核蛋白缺失的小鼠中得到增强

Michael Helwig, Michael Klinkenberg, Raffaella Rusconi, Ruth E Musgrove, Nour K Majbour, Omar M A El-Agnaf, Ayse Ulusoy, Donato A Di Monte

The neural chaperone proSAAS blocks α-synuclein fibrillation and neurotoxicity

神经伴侣 proSAAS 可阻断 α-突触核蛋白的纤维化和神经毒性

Timothy S Jarvela, Hoa A Lam, Michael Helwig, Nikolai Lorenzen, Daniel E Otzen, Pamela J McLean, Nigel T Maidment, Iris Lindberg

Neuron-to-neuron α-synuclein propagation in vivo is independent of neuronal injury

体内神经元间 α-突触核蛋白的传播与神经元损伤无关

Ayse Ulusoy, Ruth E Musgrove, Raffaella Rusconi, Michael Klinkenberg, Michael Helwig, Anja Schneider, Donato A Di Monte

A novel function for proSAAS as an amyloid anti-aggregant in Alzheimer's disease

proSAAS 作为阿尔茨海默病中淀粉样蛋白抗聚集剂的新功能

Akina Hoshino, Michael Helwig, Sina Rezaei, Casey Berridge, Jason L Eriksen, Iris Lindberg

Caudo-rostral brain spreading of α-synuclein through vagal connections

α-突触核蛋白通过迷走神经连接从尾部向大脑前部扩散

Ayse Ulusoy, Raffaella Rusconi, Blanca I Pérez-Revuelta, Ruth E Musgrove, Michael Helwig, Bettina Winzen-Reichert, Donato A Di Monte

The neuroendocrine protein 7B2 suppresses the aggregation of neurodegenerative disease-related proteins

神经内分泌蛋白 7B2 抑制神经退行性疾病相关蛋白的聚集

Michael Helwig, Akina Hoshino, Casey Berridge, Sang-Nam Lee, Nikolai Lorenzen, Daniel E Otzen, Jason L Eriksen, Iris Lindberg