The Synergistic Use of IL-15 and IL-21 for the Generation of NK Cells From CD3/CD19-Depleted Grafts Improves Their ex vivo Expansion and Cytotoxic Potential Against Neuroblastoma: Perspective for Optimized Immunotherapy Post Haploidentical Stem Cell Transplantation
IL-15 和 IL-21 协同作用,从 CD3/CD19 耗竭的移植物中生成 NK 细胞,可改善其体外扩增和对神经母细胞瘤的细胞毒性潜力:单倍体相合干细胞移植后优化免疫治疗的前景
期刊:Frontiers in Immunology
影响因子:5.7
doi:10.3389/fimmu.2019.02816
Annekathrin Heinze, Beatrice Grebe, Melanie Bremm, Sabine Huenecke, Tasleem Ah Munir, Lea Graafen, Jochen T Frueh, Michael Merker, Eva Rettinger, Jan Soerensen, Thomas Klingebiel, Peter Bader, Evelyn Ullrich, Claudia Cappel