日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The toxin biliatresone causes mouse extrahepatic cholangiocyte damage and fibrosis through decreased glutathione and SOX17

毒素比利他酮通过降低谷胱甘肽和 SOX17 导致小鼠肝外胆管细胞损伤和纤维化

Orith Waisbourd-Zinman, Hong Koh, Shannon Tsai, Pierre-Marie Lavrut, Christine Dang, Xiao Zhao, Michael Pack, Jeff Cave, Mark Hawes, Kyung A Koo, John R Porter, Rebecca G Wells

The RNA polymerase III subunit Polr3b is required for the maintenance of small intestinal crypts in mice

RNA 聚合酶 III 亚基 Polr3b 是小鼠小肠隐窝维持所必需的

Julia Kieckhaefer, Sabina Lukovac, Diana Z Ye, Dolim Lee, Danielle J Beetler, Michael Pack, Klaus H Kaestner

Graded effects of unregulated smooth muscle myosin on intestinal architecture, intestinal motility and vascular function in zebrafish

不受调节的平滑肌肌球蛋白对斑马鱼肠道结构、肠道运动和血管功能的分级影响

Joshua Abrams, Zev Einhorn, Christoph Seiler, Alan B Zong, H Lee Sweeney, Michael Pack

Identification of a plant isoflavonoid that causes biliary atresia

鉴定出一种可导致胆道闭锁的植物异黄酮

Kristin Lorent, Weilong Gong, Kyung A Koo, Orith Waisbourd-Zinman, Sara Karjoo, Xiao Zhao, Ian Sealy, Ross N Kettleborough, Derek L Stemple, Peter A Windsor, Stephen J Whittaker, John R Porter, Rebecca G Wells, Michael Pack

Oncogenic mutations in adenomatous polyposis coli (Apc) activate mechanistic target of rapamycin complex 1 (mTORC1) in mice and zebrafish

腺瘤性息肉病结肠(Apc)的致癌突变激活小鼠和斑马鱼中的雷帕霉素复合物 1(mTORC1)的机制靶点

Alexander J Valvezan, Jian Huang, Christopher J Lengner, Michael Pack, Peter S Klein

A novel keratin18 promoter that drives reporter gene expression in the intrahepatic and extrahepatic biliary system allows isolation of cell-type specific transcripts from zebrafish liver

一种新型角蛋白18启动子可驱动肝内和肝外胆道系统中的报告基因表达,从而可以从斑马鱼肝脏中分离细胞类型特异性转录本

Benjamin J Wilkins, Weilong Gong, Michael Pack

Smooth muscle tension induces invasive remodeling of the zebrafish intestine

平滑肌张力诱导斑马鱼肠道侵袭性重塑

Christoph Seiler, Gangarao Davuluri, Joshua Abrams, Fitzroy J Byfield, Paul A Janmey, Michael Pack