日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Off-Target In Vitro Profiling Demonstrates that Remdesivir Is a Highly Selective Antiviral Agent

脱靶体外分析表明瑞德西韦是一种高选择性抗病毒药物

Yili Xu, Ona Barauskas, Cynthia Kim, Darius Babusis, Eisuke Murakami, Dmytro Kornyeyev, Gary Lee, George Stepan, Michel Perron, Roy Bannister, Brian E Schultz, Roman Sakowicz, Danielle Porter, Tomas Cihlar, Joy Y Feng

GS-5734 and its parent nucleoside analog inhibit Filo-, Pneumo-, and Paramyxoviruses

GS-5734 及其母体核苷类似物可抑制丝状病毒、肺炎病毒和副粘液病毒

Michael K Lo, Robert Jordan, Aaron Arvey, Jawahar Sudhamsu, Punya Shrivastava-Ranjan, Anne L Hotard, Mike Flint, Laura K McMullan, Dustin Siegel, Michael O Clarke, Richard L Mackman, Hon C Hui, Michel Perron, Adrian S Ray, Tomas Cihlar, Stuart T Nichol, Christina F Spiropoulou

Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys

小分子GS-5734对恒河猴埃博拉病毒的治疗效果

Travis K Warren, Robert Jordan, Michael K Lo, Adrian S Ray, Richard L Mackman, Veronica Soloveva, Dustin Siegel, Michel Perron, Roy Bannister, Hon C Hui, Nate Larson, Robert Strickley, Jay Wells, Kelly S Stuthman, Sean A Van Tongeren, Nicole L Garza, Ginger Donnelly, Amy C Shurtleff, Cary J Retterer

In Vitro Antiviral Activity and Resistance Profile Characterization of the Hepatitis C Virus NS5A Inhibitor Ledipasvir

丙型肝炎病毒 NS5A 抑制剂 Ledipasvir 的体外抗病毒活性和耐药性特征

Guofeng Cheng, Yang Tian, Brian Doehle, Betty Peng, Amoreena Corsa, Yu-Jen Lee, Ruoyu Gong, Mei Yu, Bin Han, Simin Xu, Hadas Dvory-Sobol, Michel Perron, Yili Xu, Hongmei Mo, Nikos Pagratis, John O Link, William Delaney

GS-5806 Inhibits a Broad Range of Respiratory Syncytial Virus Clinical Isolates by Blocking the Virus-Cell Fusion Process

GS-5806 通过阻断病毒-细胞融合过程抑制多种呼吸道合胞病毒临床分离株

Michel Perron, Kirsten Stray, April Kinkade, Dorothy Theodore, Gary Lee, Eugene Eisenberg, Michael Sangi, Brian E Gilbert, Robert Jordan, Pedro A Piedra, Geoffery L Toms, Richard Mackman, Tomas Cihlar

Role of Mitochondrial RNA Polymerase in the Toxicity of Nucleotide Inhibitors of Hepatitis C Virus

线粒体 RNA 聚合酶在丙型肝炎病毒核苷酸抑制剂毒性中的作用

Joy Y Feng, Yili Xu, Ona Barauskas, Jason K Perry, Shekeba Ahmadyar, George Stepan, Helen Yu, Darius Babusis, Yeojin Park, Krista McCutcheon, Michel Perron, Brian E Schultz, Roman Sakowicz, Adrian S Ray

Inhibition of hepatitis C virus replication by GS-6620, a potent C-nucleoside monophosphate prodrug

GS-6620(一种有效的 C-核苷单磷酸前体药物)可抑制丙型肝炎病毒复制

Joy Y Feng, Guofeng Cheng, Jason Perry, Ona Barauskas, Yili Xu, Martijn Fenaux, Stacey Eng, Neeraj Tirunagari, Betty Peng, Mei Yu, Yang Tian, Yu-Jen Lee, George Stepan, Leanna L Lagpacan, Debi Jin, Magdeleine Hung, Karin S Ku, Bin Han, Kathryn Kitrinos, Michel Perron, Gabriel Birkus, Kelly A Wong, W