日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Pharmacodynamic markers and clinical results from the phase 2 study of the SMAC mimetic birinapant in women with relapsed platinum-resistant or -refractory epithelial ovarian cancer

SMAC 类似物 birinapant 在复发性铂耐药或难治性上皮性卵巢癌患者中的 2 期研究的药效学指标和临床结果

Anne M Noonan #, Kristen P Bunch #, Jin-Qiu Chen, Michelle A Herrmann, Jung-Min Lee, Elise C Kohn, Ciara C O'Sullivan, Elizabeth Jordan, Nicole Houston, Naoko Takebe, Robert J Kinders, Liang Cao, Cody J Peer, W Douglas Figg, Christina M Annunziata

RCC1-dependent activation of Ran accelerates cell cycle and DNA repair, inhibiting DNA damage-induced cell senescence

RCC1 依赖的 Ran 激活可加速细胞周期和 DNA 修复,抑制 DNA 损伤引起的细胞衰老

Pavol Cekan, Keisuke Hasegawa, Yu Pan, Emily Tubman, David Odde, Jin-Qiu Chen, Michelle A Herrmann, Sheetal Kumar, Petr Kalab

Biological activity of the bryostatin analog Merle 23 on mouse epidermal cells and mouse skin

苔藓抑素类似物 Merle 23 对小鼠表皮细胞和小鼠皮肤的生物活性

Jessica S Kelsey, Christophe Cataisson, Jinqiu Chen, Michelle A Herrmann, Mark E Petersen, David O Baumann, Kevin M McGowan, Stuart H Yuspa, Gary E Keck, Peter M Blumberg

Molecular systems pharmacology: isoelectric focusing signature of protein kinase Cδ provides an integrated measure of its modulation in response to ligands

分子系统药理学:蛋白激酶 Cδ 的等电聚焦特征提供了其对配体反应的调节的综合测量

Noemi Kedei, Jin-Qiu Chen, Michelle A Herrmann, Andrea Telek, Paul K Goldsmith, Mark E Petersen, Gary E Keck, Peter M Blumberg

Overlapping substrate and inhibitor specificity of human and murine ABCG2

人类和鼠类 ABCG2 的重叠底物和抑制剂特异性

Joshua Bakhsheshian, Matthew D Hall, Robert W Robey, Michelle A Herrmann, Jin-Qiu Chen, Susan E Bates, Michael M Gottesman

Biological responses to TGF-β in the mammary epithelium show a complex dependency on Smad3 gene dosage with important implications for tumor progression

乳腺上皮对 TGF-β 的生物反应表现出对 Smad3 基因剂量的复杂依赖性,这对肿瘤进展具有重要意义

Ethan A Kohn, Yu-an Yang, Zhijun Du, Yoshiko Nagano, Catherine M H Van Schyndle, Michelle A Herrmann, Madeleine Heldman, Jin-Qiu Chen, Christina H Stuelten, Kathleen C Flanders, Lalage M Wakefield