日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structure of the MRAS-SHOC2-PP1C phosphatase complex

MRAS-SHOC2-PP1C磷酸酶复合物的结构

Zachary J Hauseman #,Michelle Fodor #,Anxhela Dhembi,Jessica Viscomi,David Egli,Melusine Bleu,Stephanie Katz,Eunyoung Park,Dong Man Jang,Kathryn A Porter,Fabian Meili,Hongqiu Guo,Grainne Kerr,Sandra Mollé,Camilo Velez-Vega,Kim S Beyer,Giorgio G Galli,Saveur-Michel Maira,Travis Stams,Kirk Clark,Michael J Eck,Luca Tordella,Claudio R Thoma,Daniel A King

A capillary-based microfluidic device enables primary high-throughput room-temperature crystallographic screening

基于毛细管的微流体装置可实现初级高通量室温晶体学筛选

Shuo Sui, Anne Mulichak, Raviraj Kulathila, Joshua McGee, Danny Filiatreault, Sarthak Saha, Aina Cohen, Jinhu Song, Holly Hung, Jonathan Selway, Christina Kirby, Om K Shrestha, Wilhelm Weihofen, Michelle Fodor, Mei Xu, Rajiv Chopra, Sarah L Perry

Structural reorganization of SHP2 by oncogenic mutations and implications for oncoprotein resistance to allosteric inhibition

致癌突变导致的 SHP2 结构重组及其对癌蛋白变构抑制抗性的影响

Jonathan R LaRochelle, Michelle Fodor, Vidyasiri Vemulapalli, Morvarid Mohseni, Ping Wang, Travis Stams, Matthew J LaMarche, Rajiv Chopra, Michael G Acker, Stephen C Blacklow

ERG signaling in prostate cancer is driven through PRMT5-dependent methylation of the Androgen Receptor

前列腺癌中的 ERG 信号传导由 PRMT5 依赖的雄激素受体甲基化驱动

Zineb Mounir, Joshua M Korn, Thomas Westerling, Fallon Lin, Christina A Kirby, Markus Schirle, Gregg McAllister, Greg Hoffman, Nadire Ramadan, Anke Hartung, Yan Feng, David Randal Kipp, Christopher Quinn, Michelle Fodor, Jason Baird, Marie Schoumacher, Ronald Meyer, James Deeds, Gilles Buchwalter, T