日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

CRISPRa-mediated disentanglement of the Dux-MERVL axis in the 2C-like state, totipotency, and cell death

CRISPRa介导的Dux-MERVL轴在2C样状态、全能性和细胞死亡中的解缠。

Paul Chammas,Sheila Q Xie,Lessly P Sepulveda-Rincon,Bryony J Leeke,Marian H Dore,Dirk Dormann,Ryan T Wagner,Ning Chang,Peter L Jones,Michael T McManus,Mohammad M Karimi,George Young,Michelle Percharde

SMARCA4 regulates the NK-mediated killing of senescent cells

SMARCA4 调控 NK 细胞介导的衰老细胞杀伤作用

Virinder Reen ,Mariantonietta D'Ambrosio ,Pia Pernille Søgaard ,Katie Tyson ,Bryony J Leeke ,Isabelle Clément ,Isabel C A Dye ,Joaquim Pombo ,Adam Kuba ,Yemin Lan ,Joanna Burr ,Ida C Bomann ,Maria Kalyva ,Jodie Birch ,Sanjay Khadayate ,George Young ,Diane Provencher ,Anne-Marie Mes-Masson ,Santiago Vernia ,Nicholas McGranahan ,Hugh J M Brady ,Francis Rodier ,Raffaella Nativio ,Michelle Percharde ,Iain A McNeish ,Jesús Gil

Dynamic enlargement and mobilization of lipid droplets in pluripotent cells coordinate morphogenesis during mouse peri-implantation development

多能干细胞中脂滴的动态增大和动员协调小鼠植入前后发育过程中的形态发生

King Hang Tommy Mau, Donja Karimlou, David Barneda, Vincent Brochard, Christophe Royer, Bryony Leeke, Roshni A de Souza, Mélanie Pailles, Michelle Percharde, Shankar Srinivas, Alice Jouneau, Mark Christian, Véronique Azuara

Nucleolar-based Dux repression is essential for embryonic two-cell stage exit

基于核仁的 Dux 抑制对于胚胎退出双细胞阶段至关重要

Sheila Q Xie, Bryony J Leeke, Chad Whilding, Ryan T Wagner, Ferran Garcia-Llagostera, YiXuan Low, Paul Chammas, Nathan T-F Cheung, Dirk Dormann, Michael T McManus, Michelle Percharde

Depletion of nuclear LINE1 RNA in mouse ESCs and embryos

小鼠 ESC 和胚胎中 LINE1 RNA 的消耗

Michelle Percharde, Chih-Jen Lin, Miguel Ramalho-Santos

Genomic Repeats Categorize Genes with Distinct Functions for Orchestrated Regulation

基因组重复对具有不同功能的基因进行分类,以便进行协同调控

J Yuyang Lu, Wen Shao, Lei Chang, Yafei Yin, Tong Li, Hui Zhang, Yantao Hong, Michelle Percharde, Lerui Guo, Zhongyang Wu, Lichao Liu, Wei Liu, Pixi Yan, Miguel Ramalho-Santos, Yujie Sun, Xiaohua Shen

Delineating the early transcriptional specification of the mammalian trachea and esophagus

阐明哺乳动物气管和食管的早期转录特化

Akela Kuwahara,Ace E Lewis,Coohleen Coombes,Fang-Shiuan Leung,Michelle Percharde,Jeffrey O Bush

Maternal vitamin C regulates reprogramming of DNA methylation and germline development

母体维生素 C 调节 DNA 甲基化的重编程和生殖系发育

Stephanie P DiTroia, Michelle Percharde, Marie-Justine Guerquin, Estelle Wall, Evelyne Collignon, Kevin T Ebata, Kathryn Mesh, Swetha Mahesula, Michalis Agathocleous, Diana J Laird, Gabriel Livera, Miguel Ramalho-Santos

A LINE1-Nucleolin Partnership Regulates Early Development and ESC Identity

LINE1-核仁素伙伴关系调节早期发育和 ESC 身份

Michelle Percharde, Chih-Jen Lin, Yafei Yin, Juan Guan, Gabriel A Peixoto, Aydan Bulut-Karslioglu, Steffen Biechele, Bo Huang, Xiaohua Shen, Miguel Ramalho-Santos

The Transcriptionally Permissive Chromatin State of Embryonic Stem Cells Is Acutely Tuned to Translational Output

胚胎干细胞的转录允许染色质状态与翻译输出密切相关

Aydan Bulut-Karslioglu, Trisha A Macrae, Juan A Oses-Prieto, Sergio Covarrubias, Michelle Percharde, Gregory Ku, Aaron Diaz, Michael T McManus, Alma L Burlingame, Miguel Ramalho-Santos