Differential expression of CCR8 in tumors versus normal tissue allows specific depletion of tumor-infiltrating T regulatory cells by GS-1811, a novel Fc-optimized anti-CCR8 antibody
肿瘤与正常组织中 CCR8 的差异表达使得 GS-1811（一种新型 Fc 优化的抗 CCR8 抗体）能够特异性地消除肿瘤浸润性 T 调节细胞
期刊:Oncoimmunology
影响因子:
doi:10.1080/2162402X.2022.2141007
Jessica D Weaver, Edward C Stack, Joshua A Buggé, Changyun Hu, Lara McGrath, Amy Mueller, Masie Wong, Boris Klebanov, Tanzila Rahman, Rosemary Kaufman, Christine Fregeau, Vikki Spaulding, Michelle Priess, Kristen Legendre, Sarah Jaffe, Dhruvkumar Upadhyay, Anirudh Singh, Chang-Ai Xu, Kristin Krukenb
