日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Decoding exon inclusion in the human brain reveals more divergent splicing mechanisms in neurons than glia

对人脑外显子包含机制的解码揭示了神经元中比胶质细胞中更为多样化的剪接机制。

Michielsen, Lieke; Hsu, Justine; Joglekar, Anoushka; Belchikov, Natan; Reinders, Marcel J T; Tilgner, Hagen U; Mahfouz, Ahmed

Federated single-cell QTL meta-analysis reveals novel disease mechanisms

联合单细胞QTL荟萃分析揭示了新的疾病机制

Kaptijn, Daniel; Michielsen, Lieke; Neavin, Drew; Ripoll-Cladellas, Aida; Alquicira-Hernández, José; Korshevniuk, Maryna; Lee, Jimmy Tsz Hang; Oelen, Roy; Vochteloo, Martijn; Warmerdam, Robert; Ando, Yoshinari; Ban, Maria; Bayaraa, Odmaa; Berg, Marijn; van Blokland, Irene; Considine, Daniel; Dieng, Mame M; Edahiro, Ryuya; Gordon, M Grace; Groot, Hilde E; van der Harst, Pim; Heinig, Matthias; Hon, Chung-Chau; Idaghdour, Youssef; Kathail, Pooja; de Klein, Niek; Li, Wenchao; Li, Yang; Losert, Corinna; Manikanda, Vinu; Moody, Jonathan; Naeem, Haroon; Mokrab, Younes; Nawijn, Martijn C; Netea, Mihai; Niewold, Jelmer; Okada, Yukinori; Sawcer, Stephen; Soulama, Issiaka; Stegle, Oliver; Tsepilov, Yakov; Park, Woong-Yang; Rajagopalan, Deepa; Shahin, Tala; Shin, Jay W; Trynka, Gosia; Võsa, Urmo; Westra, Harm-Jan; Yazar, Seyhan; Ye, Jimmie; Zhang, Zhenhua; Hemberg, Martin; Mahfouz, Ahmed; Melé, Marta; Powell, Joseph E; Bonder, Marc Jan; Franke, Lude; van der Wijst, Monique G P

A unified rodent atlas reveals the cellular complexity and evolutionary divergence of the dorsal vagal complex

统一的啮齿动物图谱揭示了背侧迷走神经复合体的细胞复杂性和进化分歧。

Hes, Cecilia; Tomlinson, Abigail J; Michielsen, Lieke; Murdoch, Hunter J; Soltani, Fatemeh; Kokoeva, Maia V; Sabatini, Paul V

A spatial long-read approach at near-single-cell resolution reveals developmental regulation of splicing and polyadenylation sites in distinct cortical layers and cell types.

接近单细胞分辨率的空间长读长方法揭示了不同皮层层和细胞类型中剪接和多聚腺苷酸化位点的发育调控

Foord Careen, Prjibelski Andrey D, Hu Wen, Michielsen Lieke, Vandelli Andrea, Narykov Oleksandr, Evans Brian, Hsu Justine, Belchikov Natan, Jarroux Julien, He Yi, Ross M Elizabeth, Hajirasouliha Iman, Tartaglia Gian Gaetano, Korkin Dmitry, Tomescu Alexandru I, Tilgner Hagen U

Spatial isoform sequencing at sub-micrometer single-cell resolution reveals novel patterns of spatial isoform variability in brain cell types.

亚微米单细胞分辨率的空间同工型测序揭示了脑细胞类型中空间同工型变异的新模式

Michielsen Lieke, Prjibelski Andrey, Foord Careen, Hu Wen, Jarroux Julien, Hsu Justine, Tomescu Alexandru, Hajirasouliha Iman, Tilgner Hagen

Predicting cell population-specific gene expression from genomic sequence

从基因组序列预测细胞群体特异性基因表达

Michielsen, Lieke; Reinders, Marcel J T; Mahfouz, Ahmed

Single-cell reference mapping to construct and extend cell-type hierarchies

利用单细胞参考映射构建和扩展细胞类型层级

Michielsen, Lieke; Lotfollahi, Mohammad; Strobl, Daniel; Sikkema, Lisa; Reinders, Marcel J T; Theis, Fabian J; Mahfouz, Ahmed

Cell type matching across species using protein embeddings and transfer learning

利用蛋白质嵌入和迁移学习进行跨物种细胞类型匹配

Biharie, Kirti; Michielsen, Lieke; Reinders, Marcel J T; Mahfouz, Ahmed

Hierarchical progressive learning of cell identities in single-cell data

单细胞数据中细胞身份的分层渐进学习

Michielsen, Lieke; Reinders, Marcel J T; Mahfouz, Ahmed

A comparison of automatic cell identification methods for single-cell RNA sequencing data

单细胞RNA测序数据的自动细胞识别方法比较

Abdelaal, Tamim; Michielsen, Lieke; Cats, Davy; Hoogduin, Dylan; Mei, Hailiang; Reinders, Marcel J T; Mahfouz, Ahmed