文献库，生知库 | 链接生命科学的每一步

White Bobby, Wang Zhenyi, Dean Matthew, Michl Johanna, Nieora Natalia, Flannery Sarah, Vendrell Iolanda, Fischer Roman, Hulikova Alzbeta, Swietach Pawel

其它

低氧缺氧

发表日期：2025

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CRISPR-Cas9 screen identifies oxidative phosphorylation as essential for cancer cell survival at low extracellular pH

CRISPR-Cas9筛选发现氧化磷酸化对于癌细胞在低细胞外pH值下的存活至关重要。

期刊:Cell Reports

影响因子:6.9

doi:10.1016/j.celrep.2024.114499

Michl, Johanna; Wang, Yunyi; Monterisi, Stefania; Blaszczak, Wiktoria; Beveridge, Ryan; Bridges, Esther M; Koth, Jana; Bodmer, Walter F; Swietach, Pawel

The release of GLP-1 from gut L cells is inhibited by low extracellular pH

肠道L细胞释放GLP-1会受到低细胞外pH值的抑制。

期刊:

影响因子:

doi:10.1002/oby.24125

Garbutt, Philippa; Cyranka, Malgorzata; Michl, Johanna; Maejima, Yuko; Vedovato, Natascia; Shimomura, Kenju; Swietach, Pawel; de Wet, Heidi

A high-throughput ratiometric method for imaging hypertrophic growth in cultured primary cardiac myocytes

一种用于成像培养原代心肌细胞肥大生长的高通量比率法

期刊:Journal of Molecular and Cellular Cardiology

影响因子:4.7

doi:10.1016/j.yjmcc.2019.04.001

Loonat, Aminah A; Curtis, M Kate; Richards, Mark A; Nunez-Alonso, Graciela; Michl, Johanna; Swietach, Pawel

细胞生物学

发表日期：2019

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Interplay between Fanconi anemia and homologous recombination pathways in genome integrity

范可尼贫血与同源重组途径在基因组完整性中的相互作用

期刊:EMBO Journal

影响因子:8.3

doi:10.15252/embj.201693860

Michl, Johanna; Zimmer, Jutta; Tarsounas, Madalena

A multivariate approach linking reported side effects of clinical antidepressant and antipsychotic trials to in vitro binding affinities

将临床抗抑郁药和抗精神病药试验中报告的副作用与体外结合亲和力联系起来的多变量方法

期刊:European Neuropsychopharmacology

影响因子:6.7

doi:10.1016/j.euroneuro.2014.06.013

Michl, Johanna; Scharinger, Christian; Zauner, Miriam; Kasper, Siegfried; Freissmuth, Michael; Sitte, Harald H; Ecker, Gerhard F; Pezawas, Lukas

神经科学

发表日期：2014

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Acidosis attenuates the hypoxic stabilization of HIF-1Î± by activating lysosomal degradation.

酸中毒通过激活溶酶体降解来减弱缺氧对 HIF-1α 的稳定作用

CRISPR-Cas9 screen identifies oxidative phosphorylation as essential for cancer cell survival at low extracellular pH

CRISPR-Cas9筛选发现氧化磷酸化对于癌细胞在低细胞外pH值下的存活至关重要。

The release of GLP-1 from gut L cells is inhibited by low extracellular pH

肠道L细胞释放GLP-1会受到低细胞外pH值的抑制。

A high-throughput ratiometric method for imaging hypertrophic growth in cultured primary cardiac myocytes

一种用于成像培养原代心肌细胞肥大生长的高通量比率法

Interplay between Fanconi anemia and homologous recombination pathways in genome integrity

范可尼贫血与同源重组途径在基因组完整性中的相互作用

A multivariate approach linking reported side effects of clinical antidepressant and antipsychotic trials to in vitro binding affinities

将临床抗抑郁药和抗精神病药试验中报告的副作用与体外结合亲和力联系起来的多变量方法