日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Protein-protein interactions are a major source of epistasis in genetic interaction networks

蛋白质-蛋白质相互作用是基因相互作用网络中上位性的主要来源。

Castellanos-Girouard, Xavier; Serohijos, Adrian W R; Michnick, Stephen W

Tetravalent antibodies are more potent and efficacious erythropoiesis-stimulating agents than erythropoietin in vivo.

四价抗体在体内比促红细胞生成素更有效、更强效的促红细胞生成剂。

Adams Jarrett J, Blazer Levi L, Chung Jacky, Karimi Minoo, Davidson Taylor, Blair Bailey, Waddle Carlos, Hokanson Craig A, Bruce Heather A, Singer Alexander U, Tombak Eva-Maria, Gildemann Kiira, Tamberg Nele, Kiiver Kaja, Ustav Mart Jr, Ma Yue, Colombo Luigi, Huang Lily Jun-Shen, Michnick Stephen W, Moe Orson W, Sidhu Sachdev S

An asymmetric tetrabody is a potent and efficacious agonist of the erythropoietin receptor in vitro and in vivo.

不对称四抗体是体外和体内促红细胞生成素受体的强效激动剂

Adams Jarrett J, Blazer Levi L, Chung Jacky, Karimi Minoo, Davidson Taylor, Bruce Heather A, Singer Alexander U, Yang Ning, Cardarelli Lia, Pot Isabelle, Colombo Luigi, Huang Lily Jun-Shen, Ma Yue, Michnick Stephen W, Moe Orson W, Sidhu Sachdev S

Publisher Correction: Adaptive partitioning of a gene locus to the nuclear envelope in Saccharomyces cerevisiae is driven by polymer-polymer phase separation

出版商更正:酿酒酵母中基因位点向核膜的适应性分配是由聚合物-聚合物相分离驱动的。

González, Lidice; Kolbin, Daniel; Trahan, Christian; Jeronimo, Célia; Robert, François; Oeffinger, Marlene; Bloom, Kerry; Michnick, Stephen W

Tuberculosis and impaired IL-23-dependent IFN-γ immunity in humans homozygous for a common TYK2 missense variant

结核病和IL-23依赖性IFN-γ免疫在携带常见TYK2错义变异纯合子的人类中受损

Boisson-Dupuis, Stéphanie; Ramirez-Alejo, Noe; Li, Zhi; Patin, Etienne; Rao, Geetha; Kerner, Gaspard; Lim, Che Kang; Krementsov, Dimitry N; Hernandez, Nicholas; Ma, Cindy S; Zhang, Qian; Markle, Janet; Martinez-Barricarte, Ruben; Payne, Kathryn; Fisch, Robert; Deswarte, Caroline; Halpern, Joshua; Bouaziz, Matthieu; Mulwa, Jeanette; Sivanesan, Durga; Lazarov, Tomi; Naves, Rodrigo; Garcia, Patricia; Itan, Yuval; Boisson, Bertrand; Checchi, Alix; Jabot-Hanin, Fabienne; Cobat, Aurélie; Guennoun, Andrea; Jackson, Carolyn C; Pekcan, Sevgi; Caliskaner, Zafer; Inostroza, Jaime; Costa-Carvalho, Beatriz Tavares; de Albuquerque, Jose Antonio Tavares; Garcia-Ortiz, Humberto; Orozco, Lorena; Ozcelik, Tayfun; Abid, Ahmed; Rhorfi, Ismail Abderahmani; Souhi, Hicham; Amrani, Hicham Naji; Zegmout, Adil; Geissmann, Frédéric; Michnick, Stephen W; Muller-Fleckenstein, Ingrid; Fleckenstein, Bernhard; Puel, Anne; Ciancanelli, Michael J; Marr, Nico; Abolhassani, Hassan; Balcells, María Elvira; Condino-Neto, Antonio; Strickler, Alexis; Abarca, Katia; Teuscher, Cory; Ochs, Hans D; Reisli, Ismail; Sayar, Esra H; El-Baghdadi, Jamila; Bustamante, Jacinta; Hammarström, Lennart; Tangye, Stuart G; Pellegrini, Sandra; Quintana-Murci, Lluis; Abel, Laurent; Casanova, Jean-Laurent

Delineating functional principles of the bow tie structure of a kinase-phosphatase network in the budding yeast

阐明出芽酵母中激酶-磷酸酶网络领结结构的功能原理

Abd-Rabbo, Diala; Michnick, Stephen W

Evolution of domain-peptide interactions to coadapt specificity and affinity to functional diversity

结构域-肽相互作用的演化,共同适应功能多样性的特异性和亲和力

Kelil, Abdellali; Levy, Emmanuel D; Michnick, Stephen W

In-vivo detection of binary PKA network interactions upon activation of endogenous GPCRs

体内检测内源性GPCR激活后二元PKA网络相互作用

Röck, Ruth; Bachmann, Verena; Bhang, Hyo-Eun C; Malleshaiah, Mohan; Raffeiner, Philipp; Mayrhofer, Johanna E; Tschaikner, Philipp M; Bister, Klaus; Aanstad, Pia; Pomper, Martin G; Michnick, Stephen W; Stefan, Eduard

The dichotomous pattern of IL-12r and IL-23R expression elucidates the role of IL-12 and IL-23 in inflammation

IL-12R 和 IL-23R 表达的二分模式阐明了 IL-12 和 IL-23 在炎症中的作用。

Chognard, Gaëlle; Bellemare, Lisa; Pelletier, Adam-Nicolas; Dominguez-Punaro, Maria C; Beauchamp, Claudine; Guyon, Marie-Josée; Charron, Guy; Morin, Nicolas; Sivanesan, Durga; Kuchroo, Vijay; Xavier, Ramnik; Michnick, Stephen W; Chemtob, Sylvain; Rioux, John D; Lesage, Sylvie

Hereditary inclusion body myopathy-linked p97/VCP mutations in the NH2 domain and the D1 ring modulate p97/VCP ATPase activity and D2 ring conformation

遗传性包涵体肌病相关的p97/VCP NH2结构域和D1环突变会调节p97/VCP ATPase活性和D2环构象。

Halawani, Dalia; LeBlanc, Andréa C; Rouiller, Isabelle; Michnick, Stephen W; Servant, Marc J; Latterich, Martin