日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Deciphering the role of a SINE-VNTR-Alu retrotransposon polymorphism as a biomarker of Parkinson's disease progression.

揭示 SINE-VNTR-Alu 逆转录转座子多态性作为帕金森病进展生物标志物的作用

Fröhlich Alexander, Pfaff Abigail L, Middlehurst Ben, Hughes Lauren S, Bubb Vivien J, Quinn John P, Koks Sulev

CRISPR deletion of a SINE-VNTR-Alu (SVA_67) retrotransposon demonstrates its ability to differentially modulate gene expression at the MAPT locus

利用 CRISPR 技术删除 SINE-VNTR-Alu (SVA_67) 逆转录转座子,证明了其能够差异性地调节 MAPT 位点的基因表达。

Fröhlich, Alexander; Hughes, Lauren S; Middlehurst, Ben; Pfaff, Abigail L; Bubb, Vivien J; Koks, Sulev; Quinn, John P

A polymorphic transcriptional regulatory domain in the amyotrophic lateral sclerosis risk gene CFAP410 correlates with differential isoform expression

肌萎缩侧索硬化症风险基因CFAP410中的多态性转录调控域与差异性亚型表达相关

Marshall, Jack N G; Fröhlich, Alexander; Li, Li; Pfaff, Abigail L; Middlehurst, Ben; Spargo, Thomas P; Iacoangeli, Alfredo; Lang, Bing; Al-Chalabi, Ammar; Koks, Sulev; Bubb, Vivien J; Quinn, John P

The role of Ca2+ influx in endocytic vacuole formation in pancreatic acinar cells

Ca2+内流在胰腺腺泡细胞内吞空泡形成中的作用

Voronina, Svetlana; Collier, David; Chvanov, Michael; Middlehurst, Ben; Beckett, Alison J; Prior, Ian A; Criddle, David N; Begg, Malcolm; Mikoshiba, Katsuhiko; Sutton, Robert; Tepikin, Alexei V