日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Nanoparticle-based itaconate treatment recapitulates low-cholesterol/low-fat diet-induced atherosclerotic plaque resolution

基于纳米颗粒的衣康酸盐治疗可重现低胆固醇/低脂饮食诱导的动脉粥样硬化斑块消退作用。

Natalie E Hong ,Alice Chaplin ,Lin Di ,Anastasia Ravodina ,Graham H Bevan ,Huiyun Gao ,Courteney Asase ,Roopesh Singh Gangwar ,Mark J Cameron ,Matthew Mignery ,Olga Cherepanova ,Aloke V Finn ,Lalitha Nayak ,Andrew A Pieper ,Andrei Maiseyeu

Plaque-targeted, proteolysis-resistant, activatable and MRI-visible nano-GLP-1 receptor agonist targets smooth muscle cell differentiation in atherosclerosis

针对斑块、抗蛋白水解、可激活且 MRI 可见的纳米 GLP-1 受体激动剂靶向动脉粥样硬化中的平滑肌细胞分化

Andrei Maiseyeu, Lin Di, Anastasia Ravodina, Alma Barajas-Espinosa, Atsushi Sakamoto, Alice Chaplin, Jixin Zhong, Huiyun Gao, Matthew Mignery, Navneet Narula, Aloke V Finn, Sanjay Rajagopalan

Epidermal growth factor (EGF) triggers nuclear calcium signaling through the intranuclear phospholipase Cδ-4 (PLCδ4)

表皮生长因子 (EGF) 通过核内磷脂酶 Cδ-4 (PLCδ4) 触发核钙信号传导

Marcelo Coutinho de Miranda, Michele Angela Rodrigues, Ana Carolina de Angelis Campos, Jerusa Araújo Quintão Arantes Faria, Marianna Kunrath-Lima, Gregory A Mignery, Deborah Schechtman, Alfredo Miranda Goes, Michael H Nathanson, Dawidson A Gomes

Dysferlin forms a dimer mediated by the C2 domains and the transmembrane domain in vitro and in living cells

Dysferlin 在体外和活细胞中形成由 C2 结构域和跨膜结构域介导的二聚体

Li Xu, Sandeep Pallikkuth, Zhanjia Hou, Gregory A Mignery, Seth L Robia, Renzhi Han

The BH4 domain of Bcl-2 inhibits ER calcium release and apoptosis by binding the regulatory and coupling domain of the IP3 receptor

Bcl-2 的 BH4 结构域通过结合 IP3 受体的调节和偶联结构域来抑制内质网钙释放和细胞凋亡

Yi-Ping Rong, Geert Bultynck, Ademuyiwa S Aromolaran, Fei Zhong, Jan B Parys, Humbert De Smedt, Gregory A Mignery, H Llewelyn Roderick, Martin D Bootman, Clark W Distelhorst

Bcl-2 functionally interacts with inositol 1,4,5-trisphosphate receptors to regulate calcium release from the ER in response to inositol 1,4,5-trisphosphate

Bcl-2 与肌醇 1,4,5-三磷酸受体功能性相互作用,以调节内质网对肌醇 1,4,5-三磷酸的钙释放

Rui Chen, Ignacio Valencia, Fei Zhong, Karen S McColl, H Llewelyn Roderick, Martin D Bootman, Michael J Berridge, Stuart J Conway, Andrew B Holmes, Gregory A Mignery, Patricio Velez, Clark W Distelhorst

Activation and propagation of Ca(2+) release during excitation-contraction coupling in atrial myocytes

心房肌细胞兴奋-收缩耦联过程中Ca(2+)释放的激活和传播

Kockskämper, J; Sheehan, K A; Bare, D J; Lipsius, S L; Mignery, G A; Blatter, L A

Location of the permeation pathway in the recombinant type 1 inositol 1,4,5-trisphosphate receptor

重组型 1 型肌醇 1,4,5-三磷酸受体中渗透途径的位置

Ramos-Franco, J; Galvan, D; Mignery, G A; Fill, M

Isoform-specific function of single inositol 1,4,5-trisphosphate receptor channels

单个肌醇1,4,5-三磷酸受体通道的亚型特异性功能

Ramos-Franco, J; Fill, M; Mignery, G A

rab3 is a small GTP-binding protein exclusively localized to synaptic vesicles

rab3是一种小的GTP结合蛋白,仅定位于突触小泡。

Fischer von Mollard, G; Mignery, G A; Baumert, M; Perin, M S; Hanson, T J; Burger, P M; Jahn, R; Südhof, T C