日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The domesticated transposon protein L1TD1 associates with its ancestor L1 ORF1p to promote LINE-1 retrotransposition

驯化的转座子蛋白L1TD1与其祖先L1 ORF1p结合,促进LINE-1逆转录转座。

Gülnihal Kavaklioglu,Alexandra Podhornik,Terezia Vcelkova,Jelena Marjanovic,Mirjam A Beck,Trinh Phan-Canh,Theresia Mair,Claudia Miccolo,Aleksej Drino,Mirko Doni,Gerda Egger,Susanna Chiocca,Miha Modic,Christian Seiser

DDX18 coordinates nucleolus phase separation and nuclear organization to control the pluripotency of human embryonic stem cells

DDX18 协调核仁相分离和核组织来控制人类胚胎干细胞的多能性

Xianle Shi #, Yanjing Li #, Hongwei Zhou #, Xiukun Hou #, Jihong Yang, Vikas Malik, Francesco Faiola, Junjun Ding, Xichen Bao, Miha Modic, Weiyu Zhang, Lingyi Chen, Syed Raza Mahmood, Effie Apostolou, Feng-Chun Yang, Mingjiang Xu, Wei Xie, Xin Huang, Yong Chen, Jianlong Wang3

Poised PABP-RNA hubs implement signal-dependent mRNA decay in development

在发育过程中,预先设定的PABP-RNA枢纽能够实现信号依赖性的mRNA降解。

Miha Modic ,Klara Kuret ,Sebastian Steinhauser ,Rupert Faraway ,Emiel van Genderen ,Igor Ruiz de Los Mozos ,Jona Novljan ,Žiga Vičič ,Flora C Y Lee ,Derk Ten Berge ,Nicholas M Luscombe ,Jernej Ule

Loss of TDP-43 causes ectopic endothelial sprouting and migration defects through increased fibronectin, vcam 1 and integrin α4/β1

TDP-43 的缺失会导致异位内皮细胞发芽和迁移缺陷,这是由于纤连蛋白、vcam 1 和整合素 α4/β1 增加所致

Katrin Hipke, Bettina Pitter, Alexander Hruscha, Frauke van Bebber, Miha Modic, Vikas Bansal, Sebastian A Lewandowski, Denise Orozco, Dieter Edbauer, Stefan Bonn, Christian Haass, Ulrich Pohl, Eloi Montanez, Bettina Schmid

m6A-ELISA, a simple method for quantifying N6-methyladenosine from mRNA populations

m6A-ELISA,一种从 mRNA 群体中定量 N6-甲基腺苷的简单方法

Imke Ensinck, Theodora Sideri, Miha Modic, Charlotte Capitanchik, Claudia Vivori, Patrick Toolan-Kerr, Folkert J van Werven

Phosphorylation of the HP1β hinge region sequesters KAP1 in heterochromatin and promotes the exit from naïve pluripotency

HP1β 铰链区磷酸化将 KAP1 隔离在异染色质中,并促进其退出幼稚多能性

Weihua Qin, Enes Ugur, Christopher B Mulholland, Sebastian Bultmann, Irina Solovei, Miha Modic, Martha Smets, Michael Wierer, Ignasi Forné, Axel Imhof, M Cristina Cardoso, Heinrich Leonhardt

In vitro capture and characterization of embryonic rosette-stage pluripotency between naive and primed states

体外捕获和鉴定幼稚状态和启动状态之间胚胎玫瑰花结阶段的多能性

Alex Neagu #, Emiel van Genderen #, Irene Escudero #, Lucas Verwegen, Dorota Kurek, Johannes Lehmann, Jente Stel, René A M Dirks, Guido van Mierlo, Alex Maas, Cindy Eleveld, Yang Ge, Alexander T den Dekker, Rutger W W Brouwer, Wilfred F J van IJcken, Miha Modic, Micha Drukker, Joop H Jansen, Nicolas

Recent evolution of a TET-controlled and DPPA3/STELLA-driven pathway of passive DNA demethylation in mammals

哺乳动物中 TET 控制和 DPPA3/STELLA 驱动的被动 DNA 去甲基化途径的最新进展

Christopher B Mulholland, Atsuya Nishiyama, Joel Ryan, Ryohei Nakamura, Merve Yiğit, Ivo M Glück, Carina Trummer, Weihua Qin, Michael D Bartoschek, Franziska R Traube, Edris Parsa, Enes Ugur, Miha Modic, Aishwarya Acharya, Paul Stolz, Christoph Ziegenhain, Michael Wierer, Wolfgang Enard, Thomas Care

Distinct and stage-specific contributions of TET1 and TET2 to stepwise cytosine oxidation in the transition from naive to primed pluripotency

TET1 和 TET2 在从幼稚到成熟多能性的转变过程中对胞嘧啶氧化的不同阶段性贡献

Christopher B Mulholland, Franziska R Traube, Enes Ugur, Edris Parsa, Eva-Maria Eckl, Maximilian Schönung, Miha Modic, Michael D Bartoschek, Paul Stolz, Joel Ryan, Thomas Carell, Heinrich Leonhardt, Sebastian Bultmann

Cross-Regulation between TDP-43 and Paraspeckles Promotes Pluripotency-Differentiation Transition

TDP-43与副核斑之间的交叉调控促进多能性向分化转变

Miha Modic ,Markus Grosch ,Gregor Rot ,Silvia Schirge ,Tjasa Lepko ,Tomohiro Yamazaki ,Flora C Y Lee ,Ejona Rusha ,Dmitry Shaposhnikov ,Michael Palo ,Juliane Merl-Pham ,Davide Cacchiarelli ,Boris Rogelj ,Stefanie M Hauck ,Christian von Mering ,Alexander Meissner ,Heiko Lickert ,Tetsuro Hirose ,Jernej Ule ,Micha Drukker