Mihue相关文献与解析，生知库 | 链接生命科学的每一步

Chung, Joo-Yoon; Hong, Jisu; Yee, Su-Min; Lim, Hye Won; Lee, Dahye; Yoon, Sangwon; Lee, Seung-Hwan; Jung, Yujin; Shin, Seung Hun; Kim, Song Cheol; Lee, Chang-Han; Jang, Mihue

circRNA

细胞生物学

CAR-NK

免疫/内分泌

发表日期：2026

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One-step knock-in CAR constructs in human NK cells enable scalable, TGFÎ²1-resistant immunotherapy for solid tumors.

人类NK细胞中的一步敲入CAR构建体可实现可扩展的、TGFβ1抗性的实体瘤免疫疗法。

期刊:Theranostics

影响因子:13.3

doi:10.7150/thno.127565

Yee Su-Min, Jeong Ji Hye, Kim Daeun, Kang Sung-Bae, Yoon Hanna, Cho Hyein, Park Daechan, Jun Eunsung, Jang Mihue

Enhancing cancer killing and natural killer cell persistence by targeting NOXA, a predictor of poor patient survival.

通过靶向 NOXA（一种预示患者生存率低的指标）来增强癌细胞杀伤作用和自然杀伤细胞的持久性。

期刊:Molecular Therapy Oncology

影响因子:5.3

doi:10.1016/j.omton.2026.201152

Kang Sung-Bae, Jeong Ji Hye, Kim Seung Wook, Yoo Hyejin, Lee Seunghun, Oh Ji-Hye, Sung Chang Ohk, Lee Seung-Hwan, Jun Eunsung, Jang Mihue

Novel FRET-based Immunological Synapse Biosensor for the Prediction of Chimeric Antigen Receptor-T Cell Function

一种基于FRET的新型免疫突触生物传感器用于预测嵌合抗原受体-T细胞功能

期刊:Small Methods

影响因子:10.7

doi:10.1002/smtd.202401016

Hae Nim Lee ,Soojin Lee ,Jisu Hong ,Hyejin Yoo ,Jiyun Jeong ,Yong-Woo Kim ,Hyun Mu Shin ,Mihue Jang ,Chang-Han Lee ,Hang-Rae Kim ,Jihye Seong

Cytokines in Focus: IL-2 and IL-15 in NK Adoptive Cell Cancer Immunotherapy

细胞因子聚焦：NK细胞过继性癌症免疫疗法中的IL-2和IL-15

期刊:Immune Network

影响因子:4.1

doi:10.4110/in.2025.25.e17

Marr, Bryan; Jo, Donghyeon; Jang, Mihue; Lee, Seung-Hwan

Empowering pancreatic tumor homing with augmented anti-tumor potency of CXCR2-tethered CAR-NK cells

利用CXCR2锚定CAR-NK细胞增强抗肿瘤效力，从而增强其对胰腺肿瘤的靶向性

期刊:Molecular Therapy Oncology

影响因子:4.5

doi:10.1016/j.omton.2024.200777

Jong Hyeon Yoon,Han-Na Yoon,Hyun Ju Kang,Hyejin Yoo,Moon Jung Choi,Joo-Yoon Chung,Minkoo Seo,Minsung Kim,Si On Lim,Yong Jun Kim,Jin-Ku Lee,Mihue Jang

Synergistic therapeutic combination with a CAF inhibitor enhances CAR-NK-mediated cytotoxicity via reduction of CAF-released IL-6

与 CAF 抑制剂的协同治疗组合可通过减少 CAF 释放的 IL-6 增强 CAR-NK 介导的细胞毒性

期刊:Journal for ImmunoTherapy of Cancer

影响因子:10.3

doi:10.1136/jitc-2022-006130

Young Eun Lee #, Ga-Yeon Go #, Eun-Young Koh #, Han-Na Yoon, Minkoo Seo, Seung-Mo Hong, Ji Hye Jeong, Jin-Chul Kim, Duck Cho, Tae Sung Kim, Song Cheol Kim, Eunsung Jun, Mihue Jang

Rationally designed redirection of natural killer cells anchoring a cytotoxic ligand for pancreatic cancer treatment

合理设计自然杀伤细胞重定向锚定细胞毒性配体用于胰腺癌治疗

期刊:Journal of Controlled Release

影响因子:10.5

doi:10.1016/j.jconrel.2020.07.016

Young Eun Lee, Anna Ju, Hwi Wan Choi, Jin-Chul Kim, Eunice EunKyeong Kim, Tae Sung Kim, Hyo Jeong Kang, Sang-Yeob Kim, Jin-Young Jang, Ja-Lok Ku, Song Cheol Kim, Eunsung Jun, Mihue Jang1

Combinatorial Inhibition of Cell Surface Receptors Using Dual Aptamer-Functionalized Nanoconstructs for Cancer Treatment

使用双适体功能化纳米结构对细胞表面受体进行组合抑制以治疗癌症

期刊:Pharmaceutics

影响因子:4.9

doi:10.3390/pharmaceutics12070689

Hyojin Lee, Tae Hee Kim, Daechan Park, Mihue Jang, Justin J Chung, Soo Hyun Kim, Sang-Heon Kim, Kwan Hyi Lee, Youngmee Jung, Seung Ja Oh

Streamlined selection of cancer antigens for vaccine development through integrative multi-omics and high-content cell imaging

通过综合多组学和高内涵细胞成像简化疫苗开发中癌症抗原的选择

期刊:Scientific Reports

影响因子:3.8

doi:10.1038/s41598-020-62244-z

Ki-Cheol Han #, Daechan Park #, Shinyeong Ju, Young Eun Lee, Sun-Hee Heo, Young-Ae Kim, Ji Eun Lee, Yuna Lee, Kyong Hwa Park, Se-Ho Park, Hee Jin Lee, Cheolju Lee, Mihue Jang

Rapid CAR screening and circRNA-driven CAR-NK cells for persistent shed-resistant immunotherapy

快速CAR筛选和circRNA驱动的CAR-NK细胞用于持续性脱落耐药免疫疗法

One-step knock-in CAR constructs in human NK cells enable scalable, TGFÎ²1-resistant immunotherapy for solid tumors.

人类NK细胞中的一步敲入CAR构建体可实现可扩展的、TGFβ1抗性的实体瘤免疫疗法。

Enhancing cancer killing and natural killer cell persistence by targeting NOXA, a predictor of poor patient survival.

通过靶向 NOXA（一种预示患者生存率低的指标）来增强癌细胞杀伤作用和自然杀伤细胞的持久性。

Novel FRET-based Immunological Synapse Biosensor for the Prediction of Chimeric Antigen Receptor-T Cell Function

一种基于FRET的新型免疫突触生物传感器用于预测嵌合抗原受体-T细胞功能

Cytokines in Focus: IL-2 and IL-15 in NK Adoptive Cell Cancer Immunotherapy

细胞因子聚焦：NK细胞过继性癌症免疫疗法中的IL-2和IL-15

Empowering pancreatic tumor homing with augmented anti-tumor potency of CXCR2-tethered CAR-NK cells

利用CXCR2锚定CAR-NK细胞增强抗肿瘤效力，从而增强其对胰腺肿瘤的靶向性

Synergistic therapeutic combination with a CAF inhibitor enhances CAR-NK-mediated cytotoxicity via reduction of CAF-released IL-6

与 CAF 抑制剂的协同治疗组合可通过减少 CAF 释放的 IL-6 增强 CAR-NK 介导的细胞毒性

Rationally designed redirection of natural killer cells anchoring a cytotoxic ligand for pancreatic cancer treatment

合理设计自然杀伤细胞重定向锚定细胞毒性配体用于胰腺癌治疗

Combinatorial Inhibition of Cell Surface Receptors Using Dual Aptamer-Functionalized Nanoconstructs for Cancer Treatment

使用双适体功能化纳米结构对细胞表面受体进行组合抑制以治疗癌症

Streamlined selection of cancer antigens for vaccine development through integrative multi-omics and high-content cell imaging

通过综合多组学和高内涵细胞成像简化疫苗开发中癌症抗原的选择