Glutamine-derived aspartate is required for eIF5A hypusination-mediated translation of HIF-1α to induce the polarization of tumor-associated macrophages
谷氨酰胺衍生的天冬氨酸是eIF5A次甲基化介导的HIF-1α翻译所必需的，该翻译可诱导肿瘤相关巨噬细胞的极化。
期刊:Experimental and Molecular Medicine
影响因子:9.5
doi:10.1038/s12276-024-01214-1
Dong-Ho Kim # ,Yoo Na Kang # ,Jonghwa Jin ,Mihyang Park ,Daehoon Kim ,Ghilsuk Yoon ,Jae Won Yun ,Jaebon Lee ,Soo Young Park ,Yu Rim Lee ,Jun-Kyu Byun ,Yeon-Kyung Choi ,Keun-Gyu Park
免疫/内分泌
肿瘤免疫
表观遗传
细胞生物学
巨噬细胞
IF5
肿瘤
巨噬细胞
