Spatio-temporal transcriptomics of chromothriptic SHH-medulloblastoma identifies multiple genetic clones that resist treatment and drive relapse
对染色体碎裂型SHH髓母细胞瘤进行时空转录组学分析,鉴定出多个耐药基因克隆并导致复发
期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-024-54709-w
Ilia Kats # ,Milena Simovic-Lorenz # ,Hannah Sophia Schreiber # ,Pooja Sant ,Jan-Philipp Mallm ,Verena Körber ,Albert Li ,Pravin Velmurugan ,Sophie Heuer ,Luisa Kües ,Frauke Devens ,Martin Sill ,Manfred Jugold ,Mahmoud Moustafa ,Amir Abdollahi ,Frank Winkler ,Andrey Korshunov ,Stefan M Pfister ,Oliver Stegle ,Aurélie Ernst