日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Simultaneous targeting of PD-1 and IL-2Rβγ with radiation therapy inhibits pancreatic cancer growth and metastasis

放射疗法同时靶向PD-1和IL-2Rβγ可抑制胰腺癌的生长和转移。

期刊:Cancer Cell
影响因子:48.8
doi:10.1016/j.ccell.2023.04.001
Miles Piper ，Maureen Hoen ，Laurel B Darragh ，Michael W Knitz ，Diemmy Nguyen ，Jacob Gadwa ，Greta Durini ，Idil Karakoc ，Abby Grier ，Brooke Neupert ，Benjamin Van Court ，Khalid N M Abdelazeem ，Justin Yu ，Nicholas A Olimpo ，Sophia Corbo ，Richard Blake Ross ，Tiffany T Pham ，Molishree Joshi ，Ross M Kedl ，Anthony J Saviola ，Maria Amann ，Pablo Umaña ，Laura Codarri Deak ，Christian Klein ，Angelo D'Alessandro ，Sana D Karam
胰腺癌
IL-2
肿瘤
肿瘤免疫
PD-1
发表日期：2023
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Selective targeting of IL2Rβγ combined with radiotherapy triggers CD8- and NK-mediated immunity, abrogating metastasis in HNSCC

选择性靶向IL2Rβγ联合放射疗法可激活CD8和NK细胞介导的免疫反应，从而抑制头颈部鳞状细胞癌的转移。

期刊:Cell Reports Medicine
影响因子:11.7
doi:10.1016/j.xcrm.2023.101150
Jacob Gadwa ，Maria Amann ，Thomas E Bickett ，Michael W Knitz ，Laurel B Darragh ，Miles Piper ，Benjamin Van Court ，Sanjana Bukkapatnam ，Tiffany T Pham ，Xiao-Jing Wang ，Anthony J Saviola ，Laura Codarri Deak ，Pablo Umaña ，Christian Klein ，Angelo D'Alessandro ，Sana D Karam
免疫/内分泌
T细胞
肿瘤免疫
细胞生物学
IL2
肿瘤
CD8
发表日期：2023
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A phase I/Ib trial and biological correlate analysis of neoadjuvant SBRT with single-dose durvalumab in HPV-unrelated locally advanced HNSCC

一项 I/Ib 期临床试验和生物相关性分析，探讨 HPV 无关局部晚期 HNSCC 患者单剂量度伐单抗的新辅助 SBRT

期刊:Nature Cancer
影响因子:23.5
doi:10.1038/s43018-022-00450-6
Laurel B Darragh, Michael M Knitz, Junxiao Hu, Eric T Clambey, Jennifer Backus, Andrew Dumit, Von Samedi, Andrew Bubak, Casey Greene, Timothy Waxweiler, Sanjana Mehrotra, Shilpa Bhatia, Jacob Gadwa, Thomas Bickett, Miles Piper, Kareem Fakhoury, Arthur Liu, Joshua Petit, Daniel Bowles, Ashesh Thaker,
信号转导
发表日期：2022
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EphB4 and ephrinB2 act in opposition in the head and neck tumor microenvironment

EphB4 和 ephrinB2 在头颈部肿瘤微环境中起相反作用

期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-022-31124-7
Shilpa Bhatia, Diemmy Nguyen, Laurel B Darragh, Benjamin Van Court, Jaspreet Sharma, Michael W Knitz, Miles Piper, Sanjana Bukkapatnam, Jacob Gadwa, Thomas E Bickett, Shiv Bhuvane, Sophia Corbo, Brian Wu, Yichien Lee, Mayumi Fujita, Molishree Joshi, Lynn E Heasley, Robert L Ferris, Olga Rodriguez, C
肿瘤
发表日期：2022
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Loss of cancer cell STAT1 improves response to radiation therapy and promotes T cell activation in head and neck squamous cell carcinoma

癌细胞 STAT1 的缺失可改善对放射疗法的反应并促进头颈部鳞状细胞癌中的 T 细胞活化

期刊:Cancer Immunology Immunotherapy
影响因子:8.1
doi:10.1007/s00262-021-03059-3
Michael W Knitz, Laurel B Darragh, Thomas E Bickett, Shilpa Bhatia, Sanjana Bukkapatnam, Jacob Gadwa, Miles Piper, Sophia Corbo, Diemmy Nguyen, Benjamin Van Court, Ayman Oweida, Sana D Karam
免疫
细胞生物学
头颈癌
肿瘤细胞
JAK/STAT
发表日期：2022
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Induction of ADAM10 by Radiation Therapy Drives Fibrosis, Resistance, and Epithelial-to-Mesenchyal Transition in Pancreatic Cancer

放射疗法诱导 ADAM10 导致胰腺癌发生纤维化、耐药性和上皮间质转化

期刊:Cancer Research
影响因子:12.5
doi:10.1158/0008-5472.CAN-20-3892
Adam C Mueller #, Miles Piper #, Andrew Goodspeed, Shiv Bhuvane, Jason S Williams, Shilpa Bhatia, Andy V Phan, Benjamin Van Court, Kathryn L Zolman, Brisa Peña, Ayman J Oweida, Sara Zakem, Cheryl Meguid, Michael W Knitz, Laurel Darragh, Thomas E Bickett, Jacob Gadwa, Luisa Mestroni, Matthew R G Tayl
代谢
肿瘤
胰腺癌
发表日期：2021
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Targeting resistance to radiation-immunotherapy in cold HNSCCs by modulating the Treg-dendritic cell axis

通过调节 Treg-树突状细胞轴来靶向治疗感冒 HNSCC 对放射免疫疗法的抵抗力

期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.3
doi:10.1136/jitc-2020-001955
Michael W Knitz #, Thomas E Bickett #, Laurel B Darragh, Ayman J Oweida, Shilpa Bhatia, Benjamin Van Court, Shiv Bhuvane, Miles Piper, Jacob Gadwa, Adam C Mueller, Diemmy Nguyen, Varuna Nangia, Douglas G Osborne, Xiyuan Bai, Sarah E Ferrara, Mary-Keara Boss, Andrew Goodspeed, Matthew A Burchill, Bet
免疫
流感
树突状细胞
发表日期：2021
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Complement C3a and C5a receptor blockade modulates regulatory T cell conversion in head and neck cancer

补体 C3a 和 C5a 受体阻断剂调节头颈癌中的调节性 T 细胞转化

期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.3
doi:10.1136/jitc-2021-002585
Jacob Gadwa, Thomas E Bickett #, Laurel B Darragh #, Michael William Knitz #, Shilpa Bhatia, Miles Piper, Benjamin Van Court, Shiv Bhuvane, Diemmy Nguyen, Varuna Nangia, Emily K Kleczko, Raphael A Nemenoff, Sana D Karam
免疫
细胞生物学
头颈癌
肿瘤细胞
T Cell Receptor
发表日期：2021
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The effects of ephrinB2 signaling on proliferation and invasion in glioblastoma multiforme

EphrinB2信号对多形性胶质母细胞瘤增殖和侵袭的影响

期刊:Molecular Carcinogenesis
影响因子:3
doi:10.1002/mc.23237
Shilpa Bhatia, Sanjana Bukkapatnam, Benjamin Van Court, Andy Phan, Ayman Oweida, Jacob Gadwa, Adam C Mueller, Miles Piper, Laurel Darragh, Diemmy Nguyen, Ahmed Gilani, Michael Knitz, Thomas Bickett, Adam Green, Sujatha Venkataraman, Rajeev Vibhakar, Diana Cittelly, Sana D Karam
免疫
细胞生物学
胶质细胞
发表日期：2020
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