日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Oligomeric state of the ZIKV E protein defines protective immune responses.

ZIKV E 蛋白的寡聚状态决定了保护性免疫反应

Metz Stefan W, Thomas Ashlie, Brackbill Alex, Forsberg John, Miley Michael J, Lopez Cesar A, Lazear Helen M, Tian Shaomin, de Silva Aravinda M

P-glycoprotein targeted photodynamic therapy of chemoresistant tumors using recombinant Fab fragment conjugates

利用重组Fab片段缀合物对化疗耐药肿瘤进行P-糖蛋白靶向光动力疗法

Mao, Chengqiong; Qu, Ping; Miley, Michael J; Zhao, Yan; Li, Zibo; Ming, Xin

Nanoparticle delivery of a tetravalent E protein subunit vaccine induces balanced, type-specific neutralizing antibodies to each dengue virus serotype

纳米颗粒递送四价E蛋白亚单位疫苗可诱导针对每种登革病毒血清型的平衡型特异性中和抗体。

Metz, Stefan W; Thomas, Ashlie; Brackbill, Alex; Xianwen, Yi; Stone, Michele; Horvath, Katie; Miley, Michael J; Luft, Chris; DeSimone, Joseph M; Tian, Shaomin; de Silva, Aravinda M

In Vitro Assembly and Stabilization of Dengue and Zika Virus Envelope Protein Homo-Dimers

登革热病毒和寨卡病毒包膜蛋白同源二聚体的体外组装和稳定

Metz, Stefan W; Gallichotte, Emily N; Brackbill, Alex; Premkumar, Lakshmanane; Miley, Michael J; Baric, Ralph; de Silva, Aravinda M

Discovery of Macrocyclic Pyrimidines as MerTK-Specific Inhibitors

发现大环嘧啶类化合物作为MerTK特异性抑制剂

McIver, Andrew L; Zhang, Weihe; Liu, Qingyang; Jiang, Xinpeng; Stashko, Michael A; Nichols, James; Miley, Michael J; Norris-Drouin, Jacqueline; Machius, Mischa; DeRyckere, Deborah; Wood, Edgar; Graham, Douglas K; Earp, H Shelton; Kireev, Dmitri; Frye, Stephen V; Wang, Xiaodong

Design and Synthesis of Novel Macrocyclic Mer Tyrosine Kinase Inhibitors

新型大环酪氨酸激酶抑制剂的设计与合成

Wang, Xiaodong; Liu, Jing; Zhang, Weihe; Stashko, Michael A; Nichols, James; Miley, Michael J; Norris-Drouin, Jacqueline; Chen, Zhilong; Machius, Mischa; DeRyckere, Deborah; Wood, Edgar; Graham, Douglas K; Earp, H Shelton; Kireev, Dmitri; Frye, Stephen V

Precisely Molded Nanoparticle Displaying DENV-E Proteins Induces Robust Serotype-Specific Neutralizing Antibody Responses

精确成型的纳米颗粒展示登革病毒E蛋白,可诱导产生强效的血清型特异性中和抗体反应

Metz, Stefan W; Tian, Shaomin; Hoekstra, Gabriel; Yi, Xianwen; Stone, Michelle; Horvath, Katie; Miley, Michael J; DeSimone, Joseph; Luft, Chris J; de Silva, Aravinda M

Mutation-specific RAS oncogenicity explains NRAS codon 61 selection in melanoma

突变特异性 RAS 致癌性解释了黑色素瘤中 NRAS 61 号密码子的选择

Burd, Christin E; Liu, Wenjin; Huynh, Minh V; Waqas, Meriam A; Gillahan, James E; Clark, Kelly S; Fu, Kailing; Martin, Brit L; Jeck, William R; Souroullas, George P; Darr, David B; Zedek, Daniel C; Miley, Michael J; Baguley, Bruce C; Campbell, Sharon L; Sharpless, Norman E

Increasing sequence diversity with flexible backbone protein design: the complete redesign of a protein hydrophobic core

利用柔性骨架蛋白设计增加序列多样性:蛋白质疏水核心的完全重新设计

Murphy, Grant S; Mills, Jeffrey L; Miley, Michael J; Machius, Mischa; Szyperski, Thomas; Kuhlman, Brian

The crystal structure of human UDP-glucuronosyltransferase 2B7 C-terminal end is the first mammalian UGT target to be revealed: the significance for human UGTs from both the 1A and 2B families

人UDP-葡萄糖醛酸转移酶2B7 C端晶体结构的解析是首个被揭示的哺乳动物UGT靶标:对1A和2B家族的人类UGT均具有重要意义。

Radominska-Pandya, Anna; Bratton, Stacie M; Redinbo, Matthew R; Miley, Michael J