日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Liver GPBAR1 Associates With Immune Dysfunction in Primary Sclerosing Cholangitis and Its Activation Attenuates Cholestasis in Abcb4-/- Mice

肝脏GPBAR1与原发性硬化性胆管炎的免疫功能障碍相关，其激活可减轻Abcb4-/-小鼠的胆汁淤积

期刊:Liver International
影响因子:5.2
doi:10.1111/liv.16235
Di Giorgio, Cristina; Urbani, Ginevra; Marchianò, Silvia; Biagioli, Michele; Bordoni, Martina; Bellini, Rachele; Massa, Carmen; Lachi, Ginevra; Cari, Luigi; Morretta, Elva; Spinelli, Lucio; Monti, Maria Chiara; Sepe, Valentina; Zampella, Angela; Distrutti, Eleonora; Banales, Jesus M; Lapitz, Ainhoa; Milkiewicz, Piotr; Milkiewicz, Malgorzata; Fiorucci, Stefano
免疫/内分泌
发表日期：2025
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The Effect of Ursodeoxycholic Acid (UDCA) on Serum Expression of miR-34a and miR-506 in Patients with Chronic Cholestatic Liver Diseases.

熊去氧胆酸（UDCA）对慢性胆汁淤积性肝病患者血清中 miR-34a 和 miR-506 表达的影响

期刊:Cells
影响因子:5.2
doi:10.3390/cells14151137
Cielica Eliza, Łaba Alicja, Milkiewicz Piotr, Kruk Beata, Kempinska-Podhorodecka Agnieszka, Kłos Patrycja, Rodrigues Pedro M, Val Beatriz, Perugorria Maria J, Banales Jesus M, Milkiewicz Malgorzata
发表日期：2025
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Sex-Dependent Regulation of Liver Fibrosis in Primary Sclerosing Cholangitis: The Role of miR-125b, Androgen Receptors, TGF-β, and Apelin Signalling

原发性硬化性胆管炎中肝纤维化的性别依赖性调控：miR-125b、雄激素受体、TGF-β和Apelin信号通路的作用

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms26167784
Abramczyk, Joanna; Milkiewicz, Malgorzata; Łaba, Alicja; Milkiewicz, Piotr; Banales, Jesus M; Kempinska-Podhorodecka, Agnieszka
TGF-β
信号转导
免疫/内分泌
发表日期：2025
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Leukemia inhibitory factor promotes human cholangiopathies, and its inhibition improves cholestasis in Abcb4-/- mice

白血病抑制因子促进人类胆管病变，抑制该因子可改善Abcb4-/-小鼠的胆汁淤积。

期刊:Hepatology Communications
影响因子:4.6
doi:10.1097/HC9.0000000000000779
Di Giorgio, Cristina; Urbani, Ginevra; Massa, Carmen; Marchianò, Silvia; Biagioli, Michele; Bordoni, Martina; Lachi, Ginevra; Sensini, Benedetta; Del Sordo, Rachele; Paniconi, Francesca; Giannelli, Eleonora; Sette, Maria Rosaria; Cari, Luigi; Morretta, Elva; Monti, Maria Chiara; De Gregorio, Rosa; Sepe, Valentina; Zampella, Angela; Lapitz, Ainhoa; Milkiewicz, Piotr; Milkiewicz, Malgorzata; Banales, Jesus M; Distrutti, Eleonora; Fiorucci, Stefano
白血病
发表日期：2025
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Liquid biopsy-based protein biomarkers for risk prediction, early diagnosis, and prognostication of cholangiocarcinoma

基于液体活检的蛋白质生物标志物在胆管癌风险预测、早期诊断和预后评估中的应用

期刊:Journal of Hepatology
影响因子:33
doi:10.1016/j.jhep.2023.02.027
Lapitz, Ainhoa; Azkargorta, Mikel; Milkiewicz, Piotr; Olaizola, Paula; Zhuravleva, Ekaterina; Grimsrud, Marit M; Schramm, Christoph; Arbelaiz, Ander; O'Rourke, Colm J; La Casta, Adelaida; Milkiewicz, Malgorzata; Pastor, Tania; Vesterhus, Mette; Jimenez-Agüero, Raul; Dill, Michael T; Lamarca, Angela; Valle, Juan W; Macias, Rocio I R; Izquierdo-Sanchez, Laura; Pérez Castaño, Ylenia; Caballero-Camino, Francisco Javier; Riaño, Ioana; Krawczyk, Marcin; Ibarra, Cesar; Bustamante, Javier; Nova-Camacho, Luiz M; Falcon-Perez, Juan M; Elortza, Felix; Perugorria, Maria J; Andersen, Jesper B; Bujanda, Luis; Karlsen, Tom H; Folseraas, Trine; Rodrigues, Pedro M; Banales, Jesus M
肿瘤
胆管癌
肿瘤免疫
发表日期：2023
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The Role of hsa-miR-125b-5p Interaction with S1P/Ceramide Axis in the Potential Development of Inflammation-Associated Colon Cancer in Primary Sclerosing Cholangitis

hsa-miR-125b-5p 与 S1P/神经酰胺轴相互作用在原发性硬化性胆管炎炎症相关结肠癌潜在发展中的作用

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms24119175
Abramczyk, Joanna; Milkiewicz, Malgorzata; Hula, Bartosz; Milkiewicz, Piotr; Kempinska-Podhorodecka, Agnieszka
肿瘤
炎症
肠癌
肿瘤免疫
炎症/感染
Immunology/Inflammation
发表日期：2023
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Suppression of Hepatic PPARα in Primary Biliary Cholangitis Is Modulated by miR-155

miR-155 调节原发性胆汁性胆管炎中肝脏 PPARα 的抑制

期刊:Cells
影响因子:5.1
doi:10.3390/cells11182880
Monika Adamowicz, Agnieszka Kempinska-Podhorodecka, Joanna Abramczyk, Jesus M Banales, Piotr Milkiewicz, Malgorzata Milkiewicz
信号转导
FCM
IF
IHC-P
WB
发表日期：2022
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A common variant in the hepatobiliary phospholipid transporter ABCB4 modulates liver injury in PBC but not in PSC: prospective analysis in 867 patients

肝胆磷脂转运蛋白ABCB4的常见变异会影响原发性胆汁性胆管炎（PBC）的肝损伤，但不会影响原发性硬化性胆管炎（PSC）的肝损伤：一项纳入867例患者的前瞻性分析

期刊:Orphanet Journal of Rare Diseases
影响因子:3.5
doi:10.1186/s13023-022-02565-6
Kruk, Beata; Milkiewicz, Malgorzata; Raszeja-Wyszomirska, Joanna; Milkiewicz, Piotr; Krawczyk, Marcin
肝损伤
毒理研究
发表日期：2022
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PR3-ANCAs Detected by Third-Generation ELISA Predicts Severe Disease and Poor Survival in Primary Sclerosing Cholangitis

第三代 ELISA 检测到的 PR3-ANCA 可预测原发性硬化性胆管炎的严重疾病和不良生存率

期刊:Diagnostics
影响因子:3.3
doi:10.3390/diagnostics12112682
Lopens, Steffi; Wunsch, Ewa; Milkiewicz, Malgorzata; Röber, Nadja; Zarske, Grit; Nasser, Abdullah; Conrad, Karsten; Laass, Martin; Rödiger, Stefan; Krawczyk, Marcin; Roggenbuck, Dirk; Milkiewicz, Piotr
发表日期：2022
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Anti-glycoprotein 2 (anti-GP2) IgA and anti-neutrophil cytoplasmic antibodies to serine proteinase 3 (PR3-ANCA): antibodies to predict severe disease, poor survival and cholangiocarcinoma in primary sclerosing cholangitis

抗糖蛋白2（抗GP2）IgA和抗中性粒细胞胞浆抗体（PR3-ANCA）：可预测原发性硬化性胆管炎的严重疾病、不良预后和胆管癌的抗体

期刊:Alimentary Pharmacology & Therapeutics
影响因子:6.7
doi:10.1111/apt.16153
Wunsch, Ewa; Norman, Gary L; Milkiewicz, Malgorzata; Krawczyk, Marcin; Bentow, Chelsea; Shums, Zakera; Mahler, Michael; Lopens, Steffi; Reinhold, Dirk; Franke, Andre; Schramm, Christoph; Roggenbuck, Dirk; Milkiewicz, Piotr
IgA
中性粒细胞
肿瘤
胆管癌
细胞生物学
肿瘤免疫
粒细胞
发表日期：2021
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