Targeting the hydrophobic pocket of autotaxin with virtual screening of inhibitors identifies a common aromatic sulfonamide structural motif
通过抑制剂虚拟筛选,针对自分泌运动因子的疏水口袋,识别出常见的芳香族磺酰胺结构基序
期刊:FEBS Journal
影响因子:5.5
doi:10.1111/febs.12674
James I Fells, Sue Chin Lee, Derek D Norman, Ryoko Tsukahara, Jason R Kirby, Sandra Nelson, William Seibel, Ruben Papoian, Renukadevi Patil, Duane D Miller, Abby L Parrill, Truc-Chi Pham, Daniel L Baker, Robert Bittman, Gabor Tigyi