日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Computational design of potent and selective binders of BAK and BAX.

利用计算机设计高效选择性 BAK 和 BAX 结合剂

Berger Stephanie, Lee Erinna F, Harris Tiffany J, Tran Sharon, Bera Asim K, Arguinchona Lauren, Kang Alex, Sankaran Banumathi, Kasapgil Sila, Miller Michelle S, Smyth Sean, Lutfi Mariam, Uren Rachel T, Kluck Ruth M, Colman Peter M, Fairlie Walter D, Czabotar Peter E, Baker David, Birkinshaw Richard W

Preclinical studies show that Co-STARs combine the advantages of chimeric antigen and T cell receptors for the treatment of tumors with low antigen densities.

临床前研究表明,Co-STARs 结合了嵌合抗原和 T 细胞受体的优势,可用于治疗抗原密度低的肿瘤

Mog Brian J, Marcou Nikita, DiNapoli Sarah R, Pearlman Alexander H, Nichakawade Tushar D, Hwang Michael S, Douglass Jacqueline, Hsiue Emily Han-Chung, Glavaris Stephanie, Wright Katharine M, Konig Maximilian F, Paul Suman, Wyhs Nicolas, Ge Jiaxin, Miller Michelle S, Azurmendi P, Watson Evangeline, Pardoll Drew M, Gabelli Sandra B, Bettegowda Chetan, Papadopoulos Nickolas, Kinzler Kenneth W, Vogelstein Bert, Zhou Shibin

Structural Determinants of Isoform Selectivity in PI3K Inhibitors

PI3K抑制剂亚型选择性的结构决定因素

Miller, Michelle S; Thompson, Philip E; Gabelli, Sandra B

Getting the Most Out of Your Crystals: Data Collection at the New High-Flux, Microfocus MX Beamlines at NSLS-II

充分利用晶体:在NSLS-II新型高通量微聚焦MX光束线上进行数据采集

Miller, Michelle S; Maheshwari, Sweta; Shi, Wuxian; Gao, Yuan; Chu, Nam; Soares, Alexei S; Cole, Philip A; Amzel, L Mario; Fuchs, Martin R; Jakoncic, Jean; Gabelli, Sandra B

Kinetic and structural analyses reveal residues in phosphoinositide 3-kinase α that are critical for catalysis and substrate recognition

动力学和结构分析揭示了磷脂酰肌醇3-激酶α中对催化和底物识别至关重要的残基。

Maheshwari, Sweta; Miller, Michelle S; O'Meally, Robert; Cole, Robert N; Amzel, L Mario; Gabelli, Sandra B

Discovery of a Small-Molecule Modulator of Glycosaminoglycan Sulfation

发现一种糖胺聚糖硫酸化的小分子调节剂

Cheung, Sheldon T; Miller, Michelle S; Pacoma, Reynand; Roland, Jason; Liu, Jian; Schumacher, Andrew M; Hsieh-Wilson, Linda C

Identification of allosteric binding sites for PI3Kα oncogenic mutant specific inhibitor design

PI3Kα致癌突变体特异性抑制剂设计的变构结合位点鉴定

Miller, Michelle S; Maheshwari, Sweta; McRobb, Fiona M; Kinzler, Kenneth W; Amzel, L Mario; Vogelstein, Bert; Gabelli, Sandra B

Corrigendum to "Rapid PD-L1 detection in tumors with PET using a highly specific peptide" [Biochemical and Biophysical Research Communications 483/1 (2017) 258-263]

对“使用高特异性肽通过PET快速检测肿瘤中的PD-L1”的更正[Biochemical and Biophysical Research Communications 483/1 (2017) 258-263]

Chatterjee, Samit; Lesniak, Wojciech G; Miller, Michelle S; Lisok, Ala; Sikorska, Emilia; Wharram, Bryan; Kumar, Dhiraj; Gabrielson, Matthew; Pomper, Martin G; Gabelli, Sandra B; Nimmagadda, Sridhar

Structural basis of nSH2 regulation and lipid binding in PI3Kα

nSH2调控和PI3Kα脂质结合的结构基础

Miller, Michelle S; Schmidt-Kittler, Oleg; Bolduc, David M; Brower, Evan T; Chaves-Moreira, Daniele; Allaire, Marc; Kinzler, Kenneth W; Jennings, Ian G; Thompson, Philip E; Cole, Philip A; Amzel, L Mario; Vogelstein, Bert; Gabelli, Sandra B

EGFR exon 19 insertions: a new family of sensitizing EGFR mutations in lung adenocarcinoma

EGFR 外显子 19 插入:肺腺癌中一组新的致敏 EGFR 突变家族

Mai He, Marzia Capelletti, Khedoudja Nafa, Cai-Hong Yun, Maria E Arcila, Vincent A Miller, Michelle S Ginsberg, Binsheng Zhao, Mark G Kris, Michael J Eck, Pasi A Jänne, Marc Ladanyi, Geoffrey R Oxnard