日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

End-of-life pathology in UM-HET3 mice treated with 16 α‑hydroxyestradiol or late‑start canagliflozin

用 16α-羟基雌二醇或延迟起始卡格列净治疗的 UM-HET3 小鼠的临终病理

Snyder, Jessica M; Harrison, David E; Korstanje, Ron; Ginsburg, Brett; Reifsnyder, Peter C; Nelson, James; Leiser, Scott; Kaczorowski, Catherine; Imai, Denise M; Salmon, Adam B; Strong, Randy; Ladiges, Warren; Miller, Richard A

Drug-Based Lifespan Extension in Mice Strongly Affects Lipids Across Six Organs

药物延长小鼠寿命对六个器官的脂质有显著影响

Greenfield, Sara; Stevens, Nathaniel C; Bishop, Lauren; Rabow, Zachary; Soto, Daniela C; Abdullah, Abdali Omar; Miller, Richard A; Fiehn, Oliver

Canagliflozin Reprograms the Aging Hippocampus in Genetically Diverse UM-HET3 Mice and Attenuates Alzheimer's-Like Pathology.

卡格列净可重编程遗传多样性 UM-HET3 小鼠衰老的海马体,并减轻阿尔茨海默病样病理。

Jayarathne Hashan, Manchanayake Dulmalika Herath, Sullivan Ryan, Chimienti Nina, Kadri Omar, Gurdziel Katherine, Kim Seongho, Jang Hyejeong, Ginsburg Brett C, Miller Richard A, Yakar Shoshana, Sadagurski Marianna

A Standardized Protocol for Mouse Longevity Studies in Preclinical Drug Development

临床前药物研发中小鼠寿命研究的标准化方案

Zhavoronkov, Alex; Wang, Qian; Liu, Yujie; Hou, Wenbin; Shen, Yuelei; Wilczok, Dominika; Fortney, Kristen; Aliper, Alex; Zhang, Man; Ren, Feng; Miller, Richard A

Downregulation of the NF-κB protein p65 is a shared phenotype among most anti-aging interventions

NF-κB蛋白p65的下调是大多数抗衰老干预措施的共同表型。

Elmansi, Ahmed M; Kassem, Abraham; Castilla, Rafael M; Miller, Richard A

Correction to: Lifespan effects in male UM‑HET3 mice treated with sodium thiosulfate, 16‑hydroxyestriol, and late‑start canagliflozin

更正:用硫代硫酸钠、16-羟基雌三醇和延迟起始卡格列净治疗的雄性UM-HET3小鼠的寿命效应

Miller, Richard A; Harrison, David E; Cortopassi, Gino A; Dehghan, Ishmael; Fernandez, Elizabeth; Garratt, Michael; Geisler, John G; Ginsburg, Brett C; Han, Melissa L; Jiang, Nisi; Kaczorowski, Catherine C; Kumar, Navasuja; Leiser, Scott F; Lopez-Cruzan, Marisa; Milne, Ginger; Mitchell, James R; Nelson, James F; Reifsnyder, Peter C; Salmon, Adam B; Xu, Ziying; Korstanje, Ron; Rosenthal, Nadia; Strong, Randy

Correction to: Lifespan effects in male UM‑HET3 mice treated with sodium thiosulfate, 16-hydroxyestradiol, and late‑start canagliflozin

更正:用硫代硫酸钠、16-羟基雌二醇和延迟起始卡格列净治疗的雄性UM-HET3小鼠的寿命效应

Miller, Richard A; Harrison, David E; Cortopassi, Gino A; Dehghan, Ishmael; Fernandez, Elizabeth; Garratt, Michael; Geisler, John G; Ginsburg, Brett C; Han, Melissa L; Kaczorowski, Catherine C; Kumar, Navasuja; Leiser, Scott F; Lopez-Cruzan, Marisa; Milne, Ginger; Mitchell, James R; Nelson, James F; Reifsnyder, Peter C; Salmon, Adam B; Korstanje, Ron; Rosenthal, Nadia; Strong, Randy

Soquelitinib inhibition of IL-2-inducible T cell kinase ameliorates lung damage in murine models of systemic sclerosis

索奎替尼通过抑制IL-2诱导的T细胞激酶来改善系统性硬化症小鼠模型中的肺损伤

Boleto, Gonçalo; Cauvet, Anne; Guignabert, Christophe; Thuillet, Raphaël; Ottaviani, Mina; Tu, Ly; Hsu, Lih-Yun; Rosenbaum, James T; Miller, Richard A; Allanore, Yannick

The lifespan-extending MEK1 inhibitor trametinib promotes regulation of de novo lipogenesis enzymes by chaperone-mediated autophagy.

延长寿命的 MEK1 抑制剂曲美替尼通过分子伴侣介导的自噬促进从头脂肪生成酶的调节

Chen Jiexian, Berg Joshua, Burns Calvin M, Jia Hanyi, Li Xinna, Miller Richard A, Endicott S Joseph, Garcia Gonzalo

Joseph T. Freeman Award and Excellence in Rehabilitation of Aging Persons Award Presentations and Lectures

约瑟夫·T·弗里曼奖和老年人康复卓越奖颁奖典礼及讲座

Badenoch, Bretton; Fiehn, Oliver; Rappaport, Noa; Srivastava, Pranjal; Watanabe, Kengo; Chandrasekaran, Sriram; Miller, Richard A; Bakerjian, Debra