日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Genomic Therapy Matching in Rare and Refractory Cancers

罕见和难治性癌症的基因组治疗匹配

Lin, Frank P; Thavaneswaran, Subotheni; Grady, John P; Napier, Christine E; Kansara, Maya; Sebastian, Lucille; Kee, Damien; Desai, Jayesh; Zaheed, Milita; Chinchen, Sarah; Oakes, Samantha R; Blackburn, James; Scott, Hamish S; Glover, Anthony; Fox, Stephen B; Goldstein, David; Leo, Paul; Amanuel, Benhur; Mersiades, Antony; Millward, Michael; Brown, Michael P; Charakidis, Michail; Pokorny, Adrian M J; Craft, Paul; Espinoza, David; Grimison, Peter; Harrup, Rosemary; Joshua, Anthony M; O'Byrne, Ken; Lee, Chee Khoon; Cowley, Mark J; Ballinger, Mandy L; Simes, John; Thomas, David M

Correction: Grant et al. Low pH, High Stakes: A Narrative Review Exploring the Acid-Sensing GPR65 Pathway as a Novel Approach in Renal Cell Carcinoma. Cancers 2025, 17, 3883

更正:Grant 等人,《低 pH 值,高风险:探索酸敏感 GPR65 通路作为肾细胞癌新方法的叙述性综述》,Cancers 2025, 17, 3883

Grant, Michael; Cipriani, Barbara; Corbin, Alastair; Miller, David; Naylor, Alan; Hughes, Stuart; McCarthy, Tom; Ambarkhane, Sumeet; Memon, Danish; Millward, Michael; Pal, Sumanta; Melero, Ignacio

Garsorasib, a KRAS G12C inhibitor, with or without cetuximab, an EGFR antibody, in colorectal cancer cohorts of a phase II trial in advanced solid tumors with KRAS G12C mutation

在一项针对携带 KRAS G12C 突变的晚期实体瘤患者的 II 期临床试验中,KRAS G12C 抑制剂 Garsorasib 联合或不联合 EGFR 抗体西妥昔单抗,用于治疗结直肠癌患者。

Ruan, Dan-Yun; Wu, Hao-Xiang; Xu, Ye; Munster, Pamela N; Deng, Yanhong; Richardson, Gary; Yan, Dong; Lee, Myung-Ah; Lee, Keun-Wook; Pan, Hongming; Hager, Steven; Li, Xingya; Wei, Shaozhong; Hou, Xinfang; Underhill, Craig; Millward, Michael; Nordman, Ina; Zhang, Jingdong; Shan, Jianzhen; Han, Guohong; Grewal, Jaspreet; Gadgeel, Shirish M; Sanborn, Rachel E; Huh, Seok Jae; Hu, Xiaohua; Zhang, Yihong; Xiang, Ziyong; Luo, Laisheng; Xie, Xiaoxi; Shi, Zhe; Wang, Yaolin; Zhang, Ling; Wang, Feng; Xu, Rui-Hua

Low pH, High Stakes: A Narrative Review Exploring the Acid-Sensing GPR65 Pathway as a Novel Approach in Renal Cell Carcinoma

低pH值,高风险:探索酸敏感GPR65通路作为肾细胞癌新疗法的叙述性综述

Grant, Michael; Cipriani, Barbara; Corbin, Alastair; Miller, David; Naylor, Alan; Hughes, Stuart; McCarthy, Tom; Ambarkhane, Sumeet; Memon, Danish; Millward, Michael; Pal, Sumanta; Melero, Ignacio

Outcomes With Postrecurrence Systemic Therapy Following Adjuvant Checkpoint Inhibitor Treatment for Resected Melanoma in CheckMate 238

CheckMate 238 研究中接受辅助检查点抑制剂治疗的黑色素瘤切除术后复发患者接受全身治疗的疗效

Weber, Jeffrey; Del Vecchio, Michele; Mandalá, Mario; Gogas, Helen; Arance, Ana M; Dalle, Stephane; Cowey, C Lance; Schenker, Michael; Grob, Jean-Jacques; Chiarion-Sileni, Vanna; Márquez-Rodas, Iván; Butler, Marcus O; Di Giacomo, Anna Maria; de la Cruz-Merino, Luis; Arenberger, Petr; Atkinson, Victoria; Hill, Andrew; Fecher, Leslie A; Millward, Michael; Khushalani, Nikhil I; Queirolo, Paola; Long, Georgina V; Lobo, Maurice; Askelson, Margarita; Ascierto, Paolo A; Larkin, James

Phase I studies of davoceticept (ALPN-202), a PD-L1-dependent CD28 co-stimulator and dual PD-L1/CTLA-4 inhibitor, as monotherapy and in combination with pembrolizumab in advanced solid tumors (NEON-1 and NEON-2)

达沃西替普(ALPN-202)是一种 PD-L1 依赖性 CD28 共刺激剂和双重 PD-L1/CTLA-4 抑制剂,其作为单药疗法以及与帕博利珠单抗联合疗法治疗晚期实体瘤的 I 期研究(NEON-1 和 NEON-2)

Davar, Diwakar; Cavalcante, Ludimila; Lakhani, Nehal; Moser, Justin; Millward, Michael; McKean, Meredith; Voskoboynik, Mark; Sanborn, Rachel E; Grewal, Jaspreet S; Narayan, Ajita; Patnaik, Amita; Gainor, Justin F; Sznol, Mario; Enstrom, Amanda; Blanchfield, Lori; LeBlanc, Heidi; Thomas, Heather; Chisamore, Michael J; Peng, Stanford L; Naumovski, Allison

A signal-seeking phase 2 study of Trastuzumab emtansine in tumours harbouring HER2 amplification or mutation

一项旨在探索曲妥珠单抗-美坦新治疗HER2扩增或突变肿瘤的II期临床研究

Thavaneswaran, Subotheni; Lin, Frank; Grady, John P; Espinoza, David; Huang, Min Li; Chinchen, Sarah; Sebastian, Lucille; Kansara, Maya; Mersiades, Tony; Lee, Chee Khoon; Desai, Jayesh; Grimison, Peter; Brown, Michael; Millward, Michael; Harrup, Rosemary; O'Byrne, Ken; Nagrial, Adnan; Craft, Paul; Simes, John; Joshua, Anthony M; Thomas, David M

HLA-A01 and HLA-B27 Supertypes, but Not HLA Homozygocity, Correlate with Clinical Outcome among Patients with Non-Small Cell Lung Cancer Treated with Pembrolizumab in Combination with Chemotherapy

HLA-A01 和 HLA-B27 超型(而非 HLA 纯合性)与接受帕博利珠单抗联合化疗治疗的非小细胞肺癌患者的临床结果相关

Abed, Afaf; Reid, Anna; Law, Ngie; Millward, Michael; Gray, Elin S

The clinical utility and costs of whole-genome sequencing to detect cancer susceptibility variants-a multi-site prospective cohort study

全基因组测序在检测癌症易感变异方面的临床应用价值和成本——一项多中心前瞻性队列研究

Davidson, Aimee L; Dressel, Uwe; Norris, Sarah; Canson, Daffodil M; Glubb, Dylan M; Fortuno, Cristina; Hollway, Georgina E; Parsons, Michael T; Vidgen, Miranda E; Holmes, Oliver; Koufariotis, Lambros T; Lakis, Vanessa; Leonard, Conrad; Wood, Scott; Xu, Qinying; McCart Reed, Amy E; Pickett, Hilda A; Al-Shinnag, Mohammad K; Austin, Rachel L; Burke, Jo; Cops, Elisa J; Nichols, Cassandra B; Goodwin, Annabel; Harris, Marion T; Higgins, Megan J; Ip, Emilia L; Kiraly-Borri, Catherine; Lau, Chiyan; Mansour, Julia L; Millward, Michael W; Monnik, Melissa J; Pachter, Nicholas S; Ragunathan, Abiramy; Susman, Rachel D; Townshend, Sharron L; Trainer, Alison H; Troth, Simon L; Tucker, Katherine M; Wallis, Mathew J; Walsh, Maie; Williams, Rachel A; Winship, Ingrid M; Newell, Felicity; Tudini, Emma; Pearson, John V; Poplawski, Nicola K; Mar Fan, Helen G; James, Paul A; Spurdle, Amanda B; Waddell, Nicola; Ward, Robyn L

Adjuvant Nivolumab versus Ipilimumab in Resected Stage III/IV Melanoma: 5-Year Efficacy and Biomarker Results from CheckMate 238

辅助治疗中,纳武利尤单抗与伊匹木单抗在切除的 III/IV 期黑色素瘤中的比较:CheckMate 238 研究的 5 年疗效和生物标志物结果

Larkin, James; Del Vecchio, Michele; Mandalá, Mario; Gogas, Helen; Arance Fernandez, Ana M; Dalle, Stéphane; Cowey, Charles Lance; Schenker, Michael; Grob, Jean-Jacques; Chiarion-Sileni, Vanna; Marquez-Rodas, Ivan; Butler, Marcus O; Di Giacomo, Anna Maria; Middleton, Mark R; Lutzky, Jose; de la Cruz-Merino, Luis; Arenberger, Petr; Atkinson, Victoria; Hill, Andrew G; Fecher, Leslie A; Millward, Michael; Nathan, Paul D; Khushalani, Nikhil I; Queirolo, Paola; Ritchings, Corey; Lobo, Maurice; Askelson, Margarita; Tang, Hao; Dolfi, Sonia; Ascierto, Paolo A; Weber, Jeffrey