日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Deubiquitinase YOD1 Inhibition Suppresses DEX- and Denervation-Induced Muscle Atrophy Through MAFbx Destabilization

去泛素化酶YOD1抑制通过MAFbx不稳定抑制DEX和去神经支配诱导的肌肉萎缩

Chae, Jongbeom; Woo, Seon Min; Seo, Seung Un; Yook, Simmyung; Cho, Hyo Je; Lee, Jung Yeol; Min, Kyoung Jin; Park, Junhyeon; Ryu, Dongryeol; Kwon, Taeg Kyu

Design, Synthesis and Biological Evaluation of Pyrazolopyrimidine Derivatives as Aryl Hydrocarbon Receptor Antagonists for Colorectal Cancer Immunotherapy

吡唑并嘧啶衍生物作为芳烃受体拮抗剂在结直肠癌免疫治疗中的设计、合成及生物学评价

Choi, Byeong Wook; Lee, Jae-Eon; Jeon, Da Bin; Kim, Pyeongkeun; Lee, Gwi Bin; Parameswaran, Saravanan; Jang, Ji Yun; Chandrasekaran, Gopalakrishnan; Jeong, So Yeon; Park, Geumi; Min, Kyoung-Jin; Moon, Heegyum; Yoon, Jihyeon; Heo, Yerim; Kim, Donggun; Ahn, Se Hwan; Choi, You Jeong; Kim, Seong Soon; Yang, Jung Yoon; Bae, Myung Ae; Jeon, Yong Hyun; Choi, Seok-Yong; Ahn, Jin Hee

Phosphorylation of OTUB1 at Tyr 26 stabilizes the mTORC1 component, Raptor

OTUB1 在 Tyr 26 位点的磷酸化可稳定 mTORC1 组分 Raptor。

Seo, Seung Un; Woo, Seon Min; Kim, Min Wook; Lee, Eun-Woo; Min, Kyoung-Jin; Kwon, Taeg Kyu

Cathepsin D as a potential therapeutic target to enhance anticancer drug-induced apoptosis via RNF183-mediated destabilization of Bcl-xL in cancer cells

组织蛋白酶D作为一种潜在的治疗靶点,可通过RNF183介导的Bcl-xL不稳定化作用增强抗癌药物诱导的癌细胞凋亡。

Seo, Seung Un; Woo, Seon Min; Im, Seung-Soon; Jang, Younghoon; Han, Eugene; Kim, Sang Hyun; Lee, Hongchan; Lee, Hyun-Shik; Nam, Ju-Ock; Gabrielson, Edward; Min, Kyoung-Jin; Kwon, Taeg Kyu

Itch and autophagy-mediated NF-κB activation contributes to inhibition of cathepsin D-induced sensitizing effect on anticancer drugs

瘙痒和自噬介导的 NF-κB 激活有助于抑制组织蛋白酶 D 诱导的抗癌药物增敏作用

Seo, Seung Un; Woo, Seon Min; Min, Kyoung-Jin; Kwon, Taeg Kyu

Inhibition of cathepsin K sensitizes oxaliplatin-induced apoptotic cell death by Bax upregulation through OTUB1-mediated p53 stabilization in vitro and in vivo

抑制组织蛋白酶K可通过OTUB1介导的p53稳定作用上调Bax,从而增强奥沙利铂诱导的细胞凋亡,该过程在体外和体内均有证实。

Seo, Seung Un; Woo, Seon Min; Kim, Shin; Park, Jong-Wook; Lee, Hyun-Shik; Bae, Young-Seuk; Kim, Sang Hyun; Im, Seung-Soon; Seo, Ji Hae; Min, Kyoung-Jin; Kwon, Taeg Kyu

Premature ventricular contraction increases the risk of heart failure and ventricular tachyarrhythmia

室性早搏会增加心力衰竭和室性心律失常的风险。

Kim, Yun Gi; Choi, Yun Young; Han, Kyung-Do; Min, Kyoung Jin; Choi, Ha Young; Shim, Jaemin; Choi, Jong-Il; Kim, Young-Hoon

Inhibition of Drp1 Sensitizes Cancer Cells to Cisplatin-Induced Apoptosis through Transcriptional Inhibition of c-FLIP Expression

Drp1抑制剂通过转录抑制c-FLIP表达,增强癌细胞对顺铂诱导凋亡的敏感性。

Woo, Seon Min; Min, Kyoung-Jin; Kwon, Taeg Kyu

Arylquin 1, a potent Par-4 secretagogue, induces lysosomal membrane permeabilization-mediated non-apoptotic cell death in cancer cells.

Arylquin 1 是一种强效的 Par-4 促分泌剂,可诱导癌细胞发生溶酶体膜通透性介导的非凋亡性细胞死亡

Min Kyoung-Jin, Shahriyar Sk Abrar, Kwon Taeg Kyu

Polyunsaturated fatty acid biosynthesis pathway determines ferroptosis sensitivity in gastric cancer

多不饱和脂肪酸生物合成途径决定胃癌铁死亡敏感性

Ji-Yoon Lee, Miso Nam, Hye Young Son, Kwangbeom Hyun, Seo Young Jang, Jong Woo Kim, Min Wook Kim, Youngae Jung, Eunji Jang, Seon-Jin Yoon, Jungeun Kim, Jihye Kim, Jinho Seo, Jeong-Ki Min, Kyoung-Jin Oh, Baek-Soo Han, Won Kon Kim, Kwang-Hee Bae, Jaewhan Song, Jaehoon Kim, Yong-Min Huh, Geum-Sook Hwan