日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Aberrant intermediate alveolar epithelial cells promote pathogenic activation of lung fibroblasts in preclinical fibrosis models

异常的中间肺泡上皮细胞在临床前纤维化模型中促进肺成纤维细胞的致病性活化

Evan T Hoffman # ,Anit Shah # ,Willy Roque Barboza ,Luis R Rodriguez ,Rachna Dherwani ,Porter E Dooley ,Kasey Minakin ,Yaniv Tomer ,Lauren J Ayers ,Dakota Jones ,Aditi Murthy ,Adam Bennett ,Ana N Lange ,Pushpinder S Bawa ,Feiya Wang ,Apoorva Babu ,Katrina Chavez ,Reilly S Nakamoto ,Charlotte H Cooper ,Maria C Basil ,Micha Sam Brickman Raredon ,Darrell N Kotton ,Konstantinos-Dionysios Alysandratos ,Jeremy Katzen

Impaired AMPK control of alveolar epithelial cell metabolism promotes pulmonary fibrosis

AMPK对肺泡上皮细胞代谢的控制受损会促进肺纤维化。

Rodríguez, Luis R; Alysandratos, Konstantinos-Dionysios; Katzen, Jeremy; Murthy, Aditi; Roque Barboza, Willy; Tomer, Yaniv; Bui, Sarah; Acín-Pérez, Rebeca; Petcherski, Anton; Minakin, Kasey; Carson, Paige; Iyer, Swati; Chavez, Katrina; Cooper, Charlotte H; Babu, Apoorva; Weiner, Aaron I; Vaughan, Andrew E; Arany, Zoltan; Shirihai, Orian S; Kotton, Darrell N; Beers, Michael F

Protocol for the differentiation of human alveolar epithelial type I cells from pluripotent stem cell-derived type II-like cells.

由多能干细胞衍生的 II 型样细胞分化为人类 I 型肺泡上皮细胞的方案

Burgess Claire L, Ayers Lauren J, Minakin Kasey, Alysandratos Konstantinos-Dionysios, Varelas Xaralabos, Kotton Darrell N

Generation of human alveolar epithelial type I cells from pluripotent stem cells

利用多能干细胞生成人肺泡上皮I型细胞

Burgess, Claire L; Huang, Jessie; Bawa, Pushpinder S; Alysandratos, Konstantinos-Dionysios; Minakin, Kasey; Ayers, Lauren J; Morley, Michael P; Babu, Apoorva; Villacorta-Martin, Carlos; Yampolskaya, Maria; Hinds, Anne; Thapa, Bibek R; Wang, Feiya; Matschulat, Adeline; Mehta, Pankaj; Morrisey, Edward E; Varelas, Xaralabos; Kotton, Darrell N

Culture impact on the transcriptomic programs of primary and iPSC-derived human alveolar type 2 cells

培养对原代和 iPSC 衍生的人类肺泡 2 型细胞转录组程序的影响

Konstantinos-Dionysios Alysandratos, Carolina Garcia-de-Alba, Changfu Yao, Patrizia Pessina, Jessie Huang, Carlos Villacorta-Martin, Olivia T Hix, Kasey Minakin, Claire L Burgess, Pushpinder Bawa, Aditi Murthy, Bindu Konda, Michael F Beers, Barry R Stripp, Carla F Kim, Darrell N Kotton

Patient-specific iPSCs carrying an SFTPC mutation reveal the intrinsic alveolar epithelial dysfunction at the inception of interstitial lung disease

携带SFTPC突变的患者特异性iPSC揭示了间质性肺病早期肺泡上皮的内在功能障碍

Konstantinos-Dionysios Alysandratos ,Scott J Russo ,Anton Petcherski ,Evan P Taddeo ,Rebeca Acín-Pérez ,Carlos Villacorta-Martin ,J C Jean ,Surafel Mulugeta ,Luis R Rodriguez ,Benjamin C Blum ,Ryan M Hekman ,Olivia T Hix ,Kasey Minakin ,Marall Vedaie ,Seunghyi Kook ,Andrew M Tilston-Lunel ,Xaralabos Varelas ,Jennifer A Wambach ,F Sessions Cole ,Aaron Hamvas ,Lisa R Young ,Marc Liesa ,Andrew Emili ,Susan H Guttentag ,Orian S Shirihai ,Michael F Beers ,Darrell N Kotton