ERK2-dependent reactivation of Akt mediates the limited response of tumor cells with constitutive K-RAS activity to PI3K inhibition
ERK2 依赖的 Akt 再激活介导具有组成性 K-RAS 活性的肿瘤细胞对 PI3K 抑制的有限反应
期刊:Cancer Biology & Therapy
影响因子:4.4
doi:10.4161/cbt.27311
Mahmoud Toulany, Minjmaa Minjgee, Mohammad Saki, Marina Holler, Friedegund Meier, Wolfgang Eicheler, H Peter Rodemann
信号转导
肿瘤
肿瘤细胞
MAPK/ERK
PI3K/Akt
