日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Increased Peripheral T Stem Cell-like Memory Features in Patients with Advanced Solid Tumors Treated with Tumor-Targeting IL-12 Immunocytokine Therapy

接受肿瘤靶向IL-12免疫细胞因子治疗的晚期实体瘤患者外周T干细胞样记忆特征增强

Goswami, Meghali; Celades, Carolina; Minnar, Christine M; Khelifa, Asma S; Poppe, Lisa K; Bracken-Clarke, Dara; Toney, Nicole J; Lynch, Megan T; Marté, Jennifer L; Gameiro, Sofia R; Gulley, James L; Schlom, Jeffrey; Donahue, Renee N

Editorial: Tumor-associated tertiary lymphoid structures response during immunotherapy

社论:免疫治疗期间肿瘤相关三级淋巴结构的反应

Mauldin, Ileana Soto; Minnar, Christine Mall; Italiano, Antoine

Systemic immunostimulation induces glucocorticoid-mediated thymic involution succeeded by rebound hyperplasia which is impaired in aged recipients

全身免疫刺激诱导糖皮质激素介导的胸腺退化,随后发生反弹性增生,而老年接受者则受损

Craig P Collins, Lam T Khuat, Gail D Sckisel, Logan V Vick, Christine M Minnar, Cordelia Dunai, Catherine T Le, Brendan D Curti, Marka Crittenden, Alexander Merleev, Michael Sheng, Nelson J Chao, Emanual Maverakis, Spencer R Rosario, Arta M Monjazeb, Bruce R Blazar, Dan L Longo, Robert J Canter, Wil

Generation of murine tumor models refractory to αPD-1/-L1 therapies due to defects in antigen processing/presentation or IFNγ signaling using CRISPR/Cas9

使用 CRISPR/Cas9 生成因抗原加工/呈递或 IFNγ 信号传导缺陷而对 αPD-1/-L1 疗法有抵抗力的小鼠肿瘤模型

Paul L Chariou, Christine M Minnar, Mayank Tandon, Mary R Guest, Raj Chari, Jeffrey Schlom, Sofia R Gameiro

Exploiting an Interleukin-15 Heterodimeric Agonist (N803) for Effective Immunotherapy of Solid Malignancies

利用白细胞介素-15异二聚体激动剂(N803)进行实体恶性肿瘤的有效免疫治疗

Lui, Grace; Minnar, Christine M; Soon-Shiong, Patrick; Schlom, Jeffrey; Gameiro, Sofia R

Preclinical and clinical studies of a tumor targeting IL-12 immunocytokine

针对肿瘤的IL-12免疫细胞因子的临床前和临床研究

Minnar, Christine M; Lui, Grace; Gulley, James L; Schlom, Jeffrey; Gameiro, Sofia R

Tumor-targeted interleukin-12 synergizes with entinostat to overcome PD-1/PD-L1 blockade-resistant tumors harboring MHC-I and APM deficiencies

肿瘤靶向白细胞介素-12 与恩替诺他协同作用,以克服具有 MHC-I 和 APM 缺陷的 PD-1/PD-L1 阻断耐药肿瘤

Christine M Minnar, Paul L Chariou, Lucas A Horn, Kristin C Hicks, Claudia Palena, Jeffrey Schlom #, Sofia R Gameiro #

Tumour-targeted interleukin-12 and entinostat combination therapy improves cancer survival by reprogramming the tumour immune cell landscape

肿瘤靶向白细胞介素-12 和恩替诺特联合治疗通过重新编程肿瘤免疫细胞景观来提高癌症生存率

Kristin C Hicks, Paul L Chariou, Yohei Ozawa, Christine M Minnar, Karin M Knudson, Thomas J Meyer, Jing Bian, Margaret Cam, Jeffrey Schlom #, Sofia R Gameiro #

Analysis of the tumor microenvironment and anti-tumor efficacy of subcutaneous vs systemic delivery of the bifunctional agent bintrafusp alfa

分析皮下注射与全身给药双功能药物bintrafusp alfa对肿瘤微环境和抗肿瘤疗效的影响

Ozawa, Yohei; Hicks, Kristin C; Minnar, Christine M; Knudson, Karin M; Schlom, Jeffrey; Gameiro, Sofia R

Mouse Preclinical Cancer Immunotherapy Modeling Involving Anti-PD-1 Therapies Reveals the Need to Use Mouse Reagents to Mirror Clinical Paradigms

涉及抗PD-1疗法的鼠类临床前癌症免疫疗法模型揭示了使用鼠类试剂模拟临床范式的必要性

Monjazeb, Arta M; Wang, Ziming; Vick, Logan V; Dunai, Cordelia; Minnar, Christine; Khuat, Lam T; Murphy, William J